Now showing items 1-2 of 2

    • Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction 

      Zangi, Lior; Lui, Kathy O; von Gise, Alexander; Ma, Qing; Ebina, Wataru; Ptaszek, Leon M.; Später, Daniela; Xu, Huansheng; Tabebordbar, Mohammadsharif; Gorbatov, Rostic; Sena, Brena; Nahrendorf, Matthias; Briscoe, David Michael; Li, Ronald A; Wagers, Amy Jo; Rossi, Derrick J; Pu, William T.; Chien, Kenneth R (Nature Publishing Group, 2013)
      In a cell-free approach to regenerative therapeutics, transient application of paracrine factors in vivo could be used to alter the behavior and fate of progenitor cells to achieve sustained clinical benefits. Here we show ...
    • Rewirable gene regulatory networks in the preimplantation embryonic development of three mammalian species 

      Xie, Dan; Chen, Chieh-Chun; Ptaszek, Leon M.; Xiao, Shu; Cao, Xiaoyi; Fang, Fang; Ng, Huck H.; Lewin, Harry A.; Cowan, Chad A.; Zhong, Sheng (Cold Spring Harbor Laboratory Press, 2010)
      Mammalian preimplantation embryonic development (PED) is thought to be governed by highly conserved processes. While it had been suggested that some plasticity of conserved signaling networks exists among different mammalian ...