Now showing items 1-5 of 5

    • Functional Multipotency of Stem Cells: A Conceptual Review of Neurotrophic Factor-Based Evidence and Its Role in Translational Research 

      Kabatas, Serdar; Wakeman, Dustin R; Wang, Junmei; Snyder, Evan Y; Teng, Yang D.; Yu, Dou; Ropper, Alexander Eli; Li, Jianxue; Sullivan, Maryrose P.; Redmond, D. Eugene; Langer, Robert S.; Sidman, Richard Leon (Bentham Science Publishers, 2011)
      We here propose an updated concept of stem cells (SCs), with an emphasis on neural stem cells (NSCs). The conventional view, which has touched principally on the essential property of lineage multipotency (e.g., the ability ...
    • The impact of discrete modes of spinal cord injury on bladder muscle contractility 

      Seth, Abhishek; Chung, Yeun Goo; Kim, Daniel; Ramachandran, Aruna; Cristofaro, Vivian; Gomez III, Pablo; Tu, Duong D; Huang, Lin; Benowitz, Larry Ira; Di Vizio, Dolores; Sullivan, Maryrose P.; Adam, Rosalyn Mare (BioMed Central, 2013)
      Background: Prior studies have compared the effect of spinal cord injury elicited using distinct approaches on motor and visceral function. However, the impact of such discrete modes of injury specifically on bladder muscle ...
    • Inhibition of TNF-α Improves the Bladder Dysfunction That Is Associated With Type 2 Diabetes 

      Wang, Zongwei; Cheng, Zhiyong; Cristofaro, Vivian; Li, Jijun; Xiao, Xingyuan; Gomez, Pablo; Ge, Rongbin; Gong, Edward; Strle, Klemen; Sullivan, Maryrose P.; Adam, Rosalyn M.; White, Morris F.; Olumi, Aria F. (American Diabetes Association, 2012)
      Diabetic bladder dysfunction (DBD) is common and affects 80% of diabetic patients. However, the molecular mechanisms underlying DBD remain elusive because of a lack of appropriate animal models. We demonstrate DBD in a ...
    • Inosine Improves Neurogenic Detrusor Overactivity following Spinal Cord Injury 

      Chung, Yeun Goo; Seth, Abhishek; Doyle, Claire; Franck, Debra; Kim, Daniel; Cristofaro, Vivian; Benowitz, Larry I.; Tu, Duong D.; Estrada, Carlos R.; Mauney, Joshua R.; Sullivan, Maryrose P.; Adam, Rosalyn M. (Public Library of Science, 2015)
      Neurogenic detrusor overactivity and the associated loss of bladder control are among the most challenging complications of spinal cord injury (SCI). Anticholinergic agents are the mainstay for medical treatment of detrusor ...
    • Myosin Va Plays a Role in Nitrergic Smooth Muscle Relaxation in Gastric Fundus and Corpora Cavernosa of Penis 

      Chaudhury, Arun; Cristofaro, Vivian; Carew, Josephine A.; Goyal, Raj K.; Sullivan, Maryrose P. (Public Library of Science, 2014)
      The intracellular motor protein myosin Va is involved in nitrergic neurotransmission possibly by trafficking of neuronal nitric oxide synthase (nNOS) within the nerve terminals. In this study, we examined the role of myosin ...