Now showing items 1-9 of 9

    • FlyBase at 25: looking to the future 

      Gramates, L. Sian; Marygold, Steven J.; dos Santos, Gilberto; Urbano, Jose-Maria; Antonazzo, Giulia; Matthews, Beverley B.; Rey, Alix J.; Tabone, Christopher J.; Crosby, Madeline A.; Emmert, David B.; Falls, Kathleen; Goodman, Joshua L.; Hu, Yanhui; Ponting, Laura; Schroeder, Andrew J.; Strelets, Victor B.; Thurmond, Jim; Zhou, Pinglei (Oxford University Press, 2017)
      Since 1992, FlyBase (flybase.org) has been an essential online resource for the Drosophila research community. Concentrating on the most extensively studied species, Drosophila melanogaster, FlyBase includes information ...
    • FlyRNAi.org—the database of the Drosophila RNAi screening center and transgenic RNAi project: 2017 update 

      Hu, Yanhui; Comjean, Aram; Roesel, Charles; Vinayagam, Arunachalam; Flockhart, Ian; Zirin, Jonathan; Perkins, Lizabeth; Perrimon, Norbert; Mohr, Stephanie E. (Oxford University Press, 2017)
      The FlyRNAi database of the Drosophila RNAi Screening Center (DRSC) and Transgenic RNAi Project (TRiP) at Harvard Medical School and associated DRSC/TRiP Functional Genomics Resources website (http://fgr.hms.harvard.edu) ...
    • FlyRNAi.org—The Database of the Drosophila RNAi Screening Center: 2012 Update 

      Flockhart, Ian; Booker, Matthew; Hu, Yanhui; McElvany, Benjamin D; Gilly, Quentin Carl; Mathey-Prevot, Bernard; Perrimon, Norbert; Mohr, Stephanie (Oxford University Press, 2011)
      FlyRNAi (http://www.flyrnai.org), the database and website of the Drosophila RNAi Screening Center (DRSC) at Harvard Medical School, serves a dual role, tracking both production of reagents for RNA interference (RNAi) ...
    • A Full-Genomic Sequence-Verified Protein-Coding Gene Collection for Francisella tularensis 

      Murthy, Tal; Raphael, Jacob; Moreira, Donna; Kelley, Fontina; Taycher, Elena; Brizuela, Leonardo; LaBaer, Joshua; Petrosino, Joseph; Rolfs, Andreas; Hu, Yanhui; McCarron, Seamus; Zuo, Dongmei; Shi, Zhenwei; Jepson, Daniel Ashley; Mohr, Stephanie; Fernandez, Mauricio J. (Public Library of Science, 2007)
      The rapid development of new technologies for the high throughput (HT) study of proteins has increased the demand for comprehensive plasmid clone resources that support protein expression. These clones must be full-length, ...
    • Genetic Determinants of Phosphate Response in Drosophila 

      Bergwitz, Clemens; Wee, Mark J.; Sinha, Sumi; Huang, Joanne Hyunjung; DeRobertis, Charles; Mensah, Lawrence; Cohen, Jonathan Brewer; Friedman, Adam Amiel Laufer; Kulkarni, Meghana; Hu, Yanhui; Vinayagam, Arunachalam; Schnall-Levin, Michael; Berger, Bonnie; Perkins, Lizabeth A.; Mohr, Stephanie; Perrimon, Norbert (Public Library of Science, 2013)
      Phosphate is required for many important cellular processes and having too little phosphate or too much can cause disease and reduce life span in humans. However, the mechanisms underlying homeostatic control of extracellular ...
    • Integrating protein-protein interaction networks with phenotypes reveals signs of interactions 

      Vinayagam, Arunachalam; Zirin, Jonathan; Roesel, Charles; Hu, Yanhui; Yilmazel, Bahar; Samsonova, Anastasia A.; Neumüller, Ralph A.; Mohr, Stephanie E.; Perrimon, Norbert (2013)
      A major objective of systems biology is to organize molecular interactions as networks and to characterize information-flow within networks. We describe a computational framework to integrate protein-protein interaction ...
    • A Novel Approach to Sequence Validating Protein Expression Clones with Automated Decision Making 

      Taycher, Elena; Rolfs, Andreas; Hu, Yanhui; Zuo, Dongmei; Mohr, Stephanie; Williamson, Janice; LaBaer, Joshua (BioMed Central, 2007)
      Background: Whereas the molecular assembly of protein expression clones is readily automated and routinely accomplished in high throughput, sequence verification of these clones is still largely performed manually, an ...
    • Online GESS: prediction of miRNA-like off-target effects in large-scale RNAi screen data by seed region analysis 

      Yilmazel, Bahar; Hu, Yanhui; Sigoillot, Frederic; Smith, Jennifer A; Shamu, Caroline E; Perrimon, Norbert; Mohr, Stephanie E (BioMed Central, 2014)
      Background: RNA interference (RNAi) is an effective and important tool used to study gene function. For large-scale screens, RNAi is used to systematically down-regulate genes of interest and analyze their roles in a ...
    • Protein Structure Initiative Material Repository: an Open Shared Public Resource of Structural Genomics Plasmids for the Biological Community 

      Cormier, Catherine Y.; Kramer, Jason; Taycher, Elena; Kelley, Fontina; Fiacco, Michael; Turnbull, Greggory; LaBaer, Joshua; Mohr, Stephanie; Zuo, Dongmei; Hu, Yanhui; Rolfs, Andreas (Oxford University Press, 2009)
      The Protein Structure Initiative Material Repository (PSI-MR; http://psimr.asu.edu) provides centralized storage and distribution for the protein expression plasmids created by PSI researchers. These plasmids are a resource ...