Now showing items 1-2 of 2

    • Genomic Imprinting in the Brain: the persistent influences from Mom and Dad 

      Perez, Julio David (2015-05-20)
      Most mammalian genes are equally expressed from the two inherited parental alleles. However, a puzzling subgroup known as imprinted genes are preferentially expressed from either the maternally- or paternally-inherited ...
    • Quantitative and functional interrogation of parent-of-origin allelic expression biases in the brain 

      Perez, Julio D; Rubinstein, Nimrod D; Fernandez, Daniel E; Santoro, Stephen W; Needleman, Leigh A; Ho-Shing, Olivia; Choi, John J; Zirlinger, Mariela; Chen, Shau-Kwaun; Liu, Jun S; Dulac, Catherine (eLife Sciences Publications, Ltd, 2015)
      The maternal and paternal genomes play different roles in mammalian brains as a result of genomic imprinting, an epigenetic regulation leading to differential expression of the parental alleles of some genes. Here we ...