Browsing by Author "Gerard, Norma"

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    • C5a Receptor Deficiency Alters Energy Utilization and Fat Storage 

      Roy, Christian; Gupta, Abhishek; Fisette, Alexandre; Lapointe, Marc; Poursharifi, Pegah; Richard, Denis; Lu, HuiLing; Lu, Bao; Gerard, Norma Preckel; Gerard, Craig John; Cianflone, Katherine (Public Library of Science, 2013)
      Objective: To investigate the impact of whole body C5a receptor (C5aR) deficiency on energy metabolism and fat storage. Design: Male wildtype (WT) and C5aR knockout (C5aRKO) mice were fed a low fat (CHOW) or a high fat ...

    • The Epithelial Sodium Channel Is a Modifier of the Long-Term Nonprogressive Phenotype Associated with F508del CFTR Mutations 

      Agrawal, Pankaj; Wang, Ruobing; Li, Hongmei Lisa; Schmitz Abe, Klaus; Simone-Roach, Chantelle; Chen, Jingxin; Shi, Jiahai; Louie, Tin; Sheng, Shaohu; Towne, Meghan C.; Brainson, Christine F.; Matthay, Michael A.; Kim, Carla; Bamshad, Michael; Emond, Mary J.; Gerard, Norma; Kleyman, Thomas R.; Gerard, Craig; Kleyman, Thomas (American Thoracic Society, 2017-12)
      Cystic fibrosis (CF) remains the most lethal genetic disease in the Caucasian population. However, there is great variability in clinical phenotypes and survival times, even among patients harboring the same genotype. We ...

    • Neurokinin-1 Receptor Signalling Impacts Bone Marrow Repopulation Efficiency 

      Berger, Alexandra; Frelin, Catherine; Shah, Divya K.; Benveniste, Patricia; Herrington, Robert; Gerard, Norma Preckel; Zúñiga-Pflücker, Juan-Carlos; Iscove, Norman N.; Paige, Christopher J. (Public Library of Science, 2013)
      Tachykinins are a large group of neuropeptides with both central and peripheral activity. Despite the increasing number of studies reporting a growth supportive effect of tachykinin peptides in various in vitro stem cell ...