Browsing by Author "Wang, Weiping"
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Emi1 preferentially inhibits ubiquitin chain elongation by the anaphase promoting complex
Wang, Weiping; Kirschner, Marc W. (2013)The anaphase promoting complex (APC) is the crucial ubiquitin ligase targeting the regulatory machinery of the cell cycle. Emi1, a major modulator of APC activity, is thought to act competitively as a pseudosubstrate. We ...