Now showing items 1-3 of 3

    • Adult hippocampal neurogenesis and pattern separation in DG: a role for feedback inhibition in modulating sparseness to govern population-based coding 

      McAvoy, Kathleen; Besnard, Antoine; Sahay, Amar (Frontiers Media S.A., 2015)
      The dentate gyrus (DG) of mammals harbors neural stem cells that generate new dentate granule cells (DGCs) throughout life. Behavioral studies using the contextual fear discrimination paradigm have found that selectively ...
    • Adult neurogenesis modifies excitability of the dentate gyrus 

      Ikrar, Taruna; Guo, Nannan; He, Kaiwen; Besnard, Antoine; Levinson, Sally; Hill, Alexis; Lee, Hey-Kyoung; Hen, Rene; Xu, Xiangmin; Sahay, Amar (Frontiers Media S.A., 2013)
      Adult-born dentate granule neurons contribute to memory encoding functions of the dentate gyrus (DG) such as pattern separation. However, local circuit-mechanisms by which adult-born neurons partake in this process are ...
    • Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence 

      Choi, Sekyu; Zhang, Bing; Ma, Sai; Gonzalez Celeiro, Meryem; Stein, Daniel; Jin, Xin; Kim, Seung Tea; Kang, Yuan-Lin; Besnard, Antoine; Rezza, Amelie; Grisanti, Laura; Buenrostro, Jason; Rendl, Michael; Nahrendorf, Matthias; Sahay, Amar; Hsu, Ya-chieh (Springer Science and Business Media LLC, 2021-03-31)
      Chronic, sustained exposure to stressors can profoundly impact tissue homeostasis, although the mechanisms by which these changes occur are largely unknown. Here, we report the adrenal gland-derived stress hormone ...