Browsing by Author "Ganis, Jared Jason"
Now showing items 1-2 of 2
-
Regulators of hemoglobin switching in zebrafish and human models
Ganis, Jared Jason (2014-06-06)Hemoglobin switching is a developmental process involving the dynamic transcriptional regulation of multiple globin genes. This molecular process involves multiple layer of complexity, and elucidating new mechanisms in ... -
Zebrafish Globin Switching Occurs in Two Developmental Stages and Is Controlled by the LCR
Ganis, Jared Jason; Hsia, Nelson; Trompouki, Eirini; de Jong, Jill L.O.; DiBiase, Anthony; Lambert, Janelle S.; Jia, Zhiying; Sabo, Peter J.; Weaver, Molly; Sandstrom, Richard; Stamatoyannopoulos, John A.; Zhou, Yi; Zon, Leonard Ira (Elsevier BV, 2012)Globin gene switching is a complex, highly regulated process allowing expression of distinct globin genes at specific developmental stages. Here, for the first time, we have characterized all of the zebrafish globins based ...