Now showing items 1-3 of 3

    • Cancer Incidence following Expansion of HIV Treatment in Botswana 

      Dryden-Peterson, Scott; Medhin, Heluf; Kebabonye-Pusoentsi, Malebogo; Seage, George R.; Suneja, Gita; Kayembe, Mukendi K. A.; Mmalane, Mompati; Rebbeck, Timothy; Rider, Jennifer R.; Essex, Myron; Lockman, Shahin (Public Library of Science, 2015)
      Background: The expansion of combination antiretroviral treatment (ART) in southern Africa has dramatically reduced mortality due to AIDS-related infections, but the impact of ART on cancer incidence in the region is ...
    • Computational Reconstruction of NFκB Pathway Interaction Mechanisms during Prostate Cancer 

      Börnigen, Daniela; Tyekucheva, Svitlana; Wang, Xiaodong; Rider, Jennifer R.; Lee, Gwo-Shu; Mucci, Lorelei A.; Sweeney, Christopher; Huttenhower, Curtis (Public Library of Science, 2016)
      Molecular research in cancer is one of the largest areas of bioinformatic investigation, but it remains a challenge to understand biomolecular mechanisms in cancer-related pathways from high-throughput genomic data. This ...
    • The role of tumor metabolism as a driver of prostate cancer progression and lethal disease: results from a nested case-control study 

      Kelly, Rachel S.; Sinnott, Jennifer A.; Rider, Jennifer R.; Ebot, Ericka M.; Gerke, Travis; Bowden, Michaela; Pettersson, Andreas; Loda, Massimo; Sesso, Howard D.; Kantoff, Philip W.; Martin, Neil E.; Giovannucci, Edward L.; Tyekucheva, Svitlana; Heiden, Matthew Vander; Mucci, Lorelei A. (BioMed Central, 2016)
      Background: Understanding the biologic mechanisms underlying the development of lethal prostate cancer is critical for improved therapeutic and prevention strategies. In this study we explored the role of tumor metabolism ...