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    • Aberrant islet unfolded protein response in type 2 diabetes 

      Engin, Feyza; Nguyen, Truc; Yermalovich, Alena; Hotamisligil, Gökhan S. (Nature Publishing Group, 2014)
      The endoplasmic reticulum adapts to fluctuations in demand and copes with stress through an adaptive signaling cascade called the unfolded protein response (UPR). Accumulating evidence indicates that the canonical UPR is ...