Now showing items 1-2 of 2

    • Mechanisms of Resistance to MAPK Pathway Inhibition in RAS-Mutant Cancers 

      Wang, Belinda (2016-05-03)
      The RAS family of genes are among the most frequently mutated genes in human cancers, including nearly all pancreatic cancers, ~40% of colorectal cancers, and ~30% of lung cancers. Although most RAS-mutant cancers depend ...
    • Synthetic Lethal Interactions With Oncogenic KRAS 

      Wang, Belinda (2018-05-15)
      KRAS is one of the most frequently mutated genes across human cancers, including 96% of pancreatic cancers, 40% of colorectal cancers, and 35% of lung cancers. The majority of human cancer cell lines and tumors from ...