Now showing items 1-2 of 2

    • FRS2 Is an Oncogene in High Grade Ovarian Cancer 

      Luo, Leo Y. (2015-05-13)
      Ovarian cancer is the most common cause of gynecologic cancer death in the United States. Despite aggressive surgical cytoreduction and chemotherapy, ovarian cancer remains one of the most lethal cancer types due to advanced ...
    • PRKACA Mediates Resistance to HER2-Targeted Therapy in Breast Cancer Cells and Restores Anti-Apoptotic Signaling 

      Moody, Susan E.; Schinzel, Anna C.; Singh, Shambhavi; Izzo, Francesca; Strickland, Matthew R.; Luo, Leo; Thomas, Sapana R.; Boehm, Jesse S.; Kim, So Young; Wang, Zhigang C.; Hahn, William C. (2014)
      Targeting HER2 with antibodies or small molecule inhibitors in HER2-positive breast cancer leads to improved survival, but resistance is a common clinical problem. To uncover novel mechanisms of resistance to anti-HER2 ...