Browsing by Author "Kirienko, Natalia"
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Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection
Pellegrino, Mark W.; Nargund, Amrita M.; Kirienko, Natalia V.; Gillis, Reba; Fiorese, Christopher J.; Haynes, Cole M. (2014)Metazoans identify and eliminate bacterial pathogens in microbe-rich environments such as the intestinal lumen, however the mechanisms are unclear. Potentially, host cells employ intracellular surveillance or stress response ... -
Stimulation of Host Immune Defenses by a Small Molecule Protects C. elegans from Bacterial Infection
Pukkila-Worley, Read; Feinbaum, Rhonda Lorin; Kirienko, Natalia; Larkins-Ford, Jonah; Conery, Annie L.; Ausubel, Frederick M. (Public Library of Science, 2012)The nematode Caenorhabditis elegans offers currently untapped potential for carrying out high-throughput, live-animal screens of low molecular weight compound libraries to identify molecules that target a variety of cellular ...