Now showing items 1-2 of 2

    • Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection 

      Pellegrino, Mark W.; Nargund, Amrita M.; Kirienko, Natalia V.; Gillis, Reba; Fiorese, Christopher J.; Haynes, Cole M. (2014)
      Metazoans identify and eliminate bacterial pathogens in microbe-rich environments such as the intestinal lumen, however the mechanisms are unclear. Potentially, host cells employ intracellular surveillance or stress response ...
    • Stimulation of Host Immune Defenses by a Small Molecule Protects C. elegans from Bacterial Infection 

      Pukkila-Worley, Read; Feinbaum, Rhonda Lorin; Kirienko, Natalia; Larkins-Ford, Jonah; Conery, Annie L.; Ausubel, Frederick M. (Public Library of Science, 2012)
      The nematode Caenorhabditis elegans offers currently untapped potential for carrying out high-throughput, live-animal screens of low molecular weight compound libraries to identify molecules that target a variety of cellular ...