Browsing by Author "Chu, Catherine"

Now showing items 1-18 of 18

    • Child Neurology: Exaggerated dermal melanocytosis in a hypotonic infant: A harbinger of GM1 gangliosidosis 

      Armstrong-Javors, Amy Elizabeth; Chu, Catherine Jean (Ovid Technologies (Wolters Kluwer Health), 2014)
      Gangliosidoses are a group of rare lysosomal storage diseases (LySD) involving the accumulation of lipids in multiple organ systems, including the central and peripheral nervous systems. These disorders are inherited in ...

    • Clobazam as an adjunctive therapy in treating seizures associated with Lennox–Gastaut syndrome 

      Fisher, Janet; Chu, Catherine Jean; Leahy, Jennifer (Dove Medical Press Ltd., 2011)
      Lennox–Gastaut syndrome (LGS) is a devastating childhood epilepsy syndrome characterized by the occurrence of multiple types of seizures and cognitive decline. Most children suffer from frequent seizures that are refractory ...

    • EEG functional connectivity is partially predicted by underlying white matter connectivity 

      Chu, Catherine Jean; Tanaka, Naoaki; Diaz, J.; Edlow, Brian Lewis; Wu, Ona; Hamalainen, Matti S.; Stufflebeam, Steven Marshall; Cash, Sydney S.; Kramer, M.A. (Elsevier BV, 2015)
      Over the past decade, networks have become a leading model to illustrate both the anatomical relationships (structural networks) and the coupling of dynamic physiology (functional networks) linking separate brain regions. ...

    • Emergence of Stable Functional Networks in Long-Term Human Electroencephalography 

      Chu, Catherine Jean; Kramer, Mark R.; Pathmanathan, Jay Sriram; Bianchi, Matt Travis; Westover, Michael Brandon; Wizon, L.; Cash, Sydney S. (Society for Neuroscience, 2012)
      Functional connectivity networks have become a central focus in neuroscience because they reveal key higher-dimensional features of normal and abnormal nervous system physiology. Functional networks reflect activity-based ...

    • High density EEG—What do we have to lose? 

      Chu, Catherine Jean (Elsevier BV, 2015)

    • Human seizures self-terminate across spatial scales via a critical transition 

      Kramer, M. A.; Truccolo, W.; Eden, U. T.; Lepage, K. Q.; Hochberg, Leigh Robert; Eskandar, Emad; Madsen, Joseph Russell; Lee, Jong Woo; Maheshwari, A.; Halgren, E.; Chu, Catherine Jean; Cash, Sydney S. (Proceedings of the National Academy of Sciences, 2012)
      Why seizures spontaneously terminate remains an unanswered fundamental question of epileptology. Here we present evidence that seizures self-terminate via a discontinuous critical transition or bifurcation. We show that ...

    • The maturation of cortical sleep rhythms and networks over early development 

      Chu, Catherine Jean; Leahy, J.; Pathmanathan, Jay Sriram; Kramer, M.A.; Cash, Sydney S. (Elsevier BV, 2014)
      Objective: Although neuronal activity drives all aspects of cortical development, how human brain rhythms spontaneously mature remains an active area of research. We sought to systematically evaluate the emergence of human ...

    • Motor Skills Training Enhances Lesion-Induced Structural Plasticity in the Motor Cortex of Adult Rats 

      Jones, Theresa A.; Chu, Catherine Jean; Grande, Lucinda A.; Gregory, Aurora D. (Society for Neuroscience, 1999)
      To assess behavioral experience effects on synaptic plasticity after brain damage, the present study examined the effects of complex motor skills training (the acrobatic task) on synaptic changes in layer V of the motor ...

    • The natural history of epilepsy in tuberous sclerosis complex 

      Chu, Catherine Jean; Major, Philippe; Camposano, Susana; Muzykewicz, David; Thiele, Elizabeth Anne (Wiley-Blackwell, 2009)
      Background: Although epilepsy affects most patients with tuberous sclerosis complex (TSC), little is known about the natural history of epilepsy in this genetic disease. Methods: A retrospective chart review of all ...

    • Network Analysis: Applications for the Developing Brain 

      Chu, Catherine Jean; Kramer, M. A.; Bianchi, Matt Travis; Caviness, Verne Strudwick; Cash, Sydney S. (SAGE Publications, 2011)
      Development of the human brain follows a complex trajectory of age-specific anatomical and physiological changes. The application of network analysis provides an illuminating perspective on the dynamic interregional and ...

    • Phylogenetic and epidemiologic evidence of multiyear incubation in human rabies 

      Boland, Torrey A.; McGuone, Declan; Jindal, Jenelle; Rocha, Marcelo; Cumming, Melissa; Rupprecht, Charles E.; Barbosa, Taciana Fernandes Souza; de Novaes Oliveira, Rafael; Chu, Catherine Jean; Cole, Andrew James; Kotait, Ivanete; Kuzmina, Natalia A.; Yager, Pamela A.; Kuzmin, Ivan V.; Hedley-Whyte, E. Tessa; Brown, Catherine M.; Rosenthal, Eric Scott (Wiley-Blackwell, 2014)
      Eight years after emigrating from Brazil, an otherwise healthy man developed rabies. An exposure prior to immigration was reported. Genetic analysis revealed a canine rabies virus variant found only in the patient’s home ...

    • Physiological consequences of abnormal connectivity in a developmental epilepsy 

      Shafi, Mouhsin; Vernet, Marine; Klooster, Debby; Chu, Catherine Jean; Boric, Katica; Barnard, Mollie E.; Romatoski, Kelsey; Westover, Michael Brandon; Christodoulou, Joanna A.; Gabrieli, John D. E.; Whitfield-Gabrieli, Susan; Pascual-Leone, Alvaro; Chang, Bernard Shaw-Farn (Wiley-Blackwell, 2015)
      Objective: Many forms of epilepsy are associated with aberrant neuronal connections, but the relationship between such pathological connectivity and the underlying physiological predisposition to seizures is unclear. We ...

    • The probability of seizures during EEG monitoring in critically ill adults 

      Westover, Michael Brandon; Shafi, Mouhsin; Bianchi, Matt Travis; Moura, Lidia M.V.R.; O’Rourke, Deirdre; Rosenthal, Eric Scott; Chu, Catherine Jean; Donovan, Samantha; Hoch, Daniel B.; Kilbride, Ronan D.; Cole, Andrew James; Cash, Sydney S. (Elsevier BV, 2015)
      Objective: To characterize the risk for seizures over time in relation to EEG findings in hospitalized adults undergoing continuous EEG monitoring (cEEG). Methods: Retrospective analysis of cEEG data and medical records ...

    • Robust disruptions in electroencephalogram cortical oscillations and large-scale functional networks in autism 

      Matlis, Sean; Boric, Katica; Chu, Catherine J.; Kramer, Mark A. (BioMed Central, 2015)
      Background: Autism spectrum disorders (ASD) are increasingly prevalent and have a significant impact on the lives of patients and their families. Currently, the diagnosis is determined by clinical judgment and no definitive ...

    • Safety and efficacy of levetiracetam for the treatment of partial onset seizures in children from one month of age 

      Chu, Catherine Jean; Cormier, undefined (Dove Medical Press Ltd., 2013)
      Epilepsy is a common neurological disorder in the pediatric population, affecting up to one percent of children, and for which the mainstay of treatment is anticonvulsant medication. Despite the frequent use of anticonvulsant ...

    • The Spatiotemporal Dynamics of Oscillatory Activity in Humans Across Micro, Meso, and Macro Scales 

      Borzello, Mia; Chu, Catherine Jean; Ebrahim, S; Eskandar, Emad; Golby, Alexandra Jacqueline; Madsen, Joseph Russell; Andersen, W; Lee, Jane; Doyle, W; Thesen, T; Cash, Sydney S. (2016-11-16)
      Brain activity is characterized by oscillatory activity that spans at least two orders of magnitude. Previous investigations of the spatiotemporal dynamics of this wide range of oscillatory behavior has led to the concept ...

    • The standardization debate: A conflation trap in critical care electroencephalography 

      Ng, Marcus C.; Gaspard, Nicolas; Cole, Andrew James; Hoch, Daniel B.; Cash, Sydney S.; Bianchi, Matt Travis; O’Rourke, Deirdre A.; Rosenthal, Eric Scott; Chu, Catherine Jean; Westover, Michael Brandon (Elsevier BV, 2015)
      Purpose: Persistent uncertainty over the clinical significance of various pathological continuous electroencephalography (cEEG) findings in the intensive care unit (ICU) has prompted efforts to standardize ICU cEEG terminology ...

    • A statistically robust EEG re-referencing procedure to mitigate reference effect 

      Lepage, Kyle Q.; Kramer, Mark Nathan; Chu, Catherine Jean (Elsevier BV, 2014)
      Background: The electroencephalogram (EEG) remains the primary tool for diagnosis of abnormal brain activity in clinical neurology and for in vivo recordings of human neurophysiology in neuroscience research. In EEG data ...