Browsing by Author "Scharfe, Charlotta"
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Structure and Sequence Analyses of Clustered Protocadherins Reveal Antiparallel Interactions that Mediate Homophilic Specificity
Nicoludis, John Michael; Lau, Sze-Yi; Scharfe, Charlotta; Marks, Debora; Weihofen, Wilhelm; Gaudet, Rachelle (Elsevier BV, 2015)Clustered protocadherin (Pcdh) proteins mediate dendritic self-avoidance in neurons via specific homophilic interactions in their extracellular cadherin (EC) domains. We determined crystal structures of EC1–EC3, containing ...