Browsing by Author "Lutz, Sharon"

Now showing items 1-3 of 3

    • Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD 

      Sun, Wei; Kechris, Katerina; Jacobson, Sean; Drummond, M. Bradley; Hawkins, Gregory A.; Yang, Jenny; Chen, Ting-huei; Quibrera, Pedro Miguel; Anderson, Wayne; Barr, R. Graham; Basta, Patricia V.; Bleecker, Eugene R.; Beaty, Terri; Casaburi, Richard; Castaldi, Peter; Cho, Michael H.; Comellas, Alejandro; Crapo, James D.; Criner, Gerard; Demeo, Dawn; Christenson, Stephanie A.; Couper, David J.; Curtis, Jeffrey L.; Doerschuk, Claire M.; Freeman, Christine M.; Gouskova, Natalia A.; Han, MeiLan K.; Hanania, Nicola A.; Hansel, Nadia N.; Hersh, Craig P.; Hoffman, Eric A.; Kaner, Robert J.; Kanner, Richard E.; Kleerup, Eric C.; Lutz, Sharon; Martinez, Fernando J.; Meyers, Deborah A.; Peters, Stephen P.; Regan, Elizabeth A.; Rennard, Stephen I.; Scholand, Mary Beth; Silverman, Edwin K.; Woodruff, Prescott G.; O’Neal, Wanda K.; Bowler, Russell P. (Public Library of Science, 2016)
      Implementing precision medicine for complex diseases such as chronic obstructive lung disease (COPD) will require extensive use of biomarkers and an in-depth understanding of how genetic, epigenetic, and environmental ...

    • A general semi-parametric approach to the analysis of genetic association studies in population-based designs 

      Lutz, Sharon; Yip, Wai-Ki; Hokanson, John; Laird, Nan M.; Lange, Christoph (BioMed Central, 2013)
      Background: For genetic association studies in designs of unrelated individuals, current statistical methodology typically models the phenotype of interest as a function of the genotype and assumes a known statistical model ...

    • Paired inspiratory-expiratory chest CT scans to assess for small airways disease in COPD 

      Hersh, Craig Palmer; Washko, George Richard; Estépar, Raúl San José; Lutz, Sharon; Friedman, Paul J; Han, MeiLan K; Hokanson, John E; Judy, Philip Frank; Lynch, David A; Make, Barry J; Marchetti, Nathaniel; Newell, John D; Sciurba, Frank C; Crapo, James D; Silverman, Edwin Kepner (BioMed Central, 2013)
      Background: Gas trapping quantified on chest CT scans has been proposed as a surrogate for small airway disease in COPD. We sought to determine if measurements using paired inspiratory and expiratory CT scans may be better ...