Browsing by Author "Rentz, Dorene"

Now showing items 1-16 of 16

    • Age-related changes in early novelty processing as measured by ERPs 

      Riis, Jenna L.; Chong, Hyemi; McGinnnis, Scott; Tarbi, Elise; Sun, Xue; Holcomb, Phillip J.; Rentz, Dorene May; Daffner, Kirk R. (Elsevier BV, 2009)
      This study investigated age-related changes in the early processing of novel visual stimuli using ERPs. Well-matched old (n=30), middle-aged (n=30), and young (n=32) subjects were presented standard, target/rare, and ...

    • Age-Related Differences in Attention to Novelty Among Cognitively High Performing Adults 

      Daffner, Kirk R.; Ryan, Katherine K.; Williams, Danielle M.; Budson, Andrew E.; Rentz, Dorene May; Wolk, David A.; Holcomb, Phillip J.; Ryan, Katherine (Elsevier BV, 2006)
      Age-related differences in attention to novel events were studied in well-matched, cognitively high performing old, middle-aged and young subjects. Event-related potentials were recorded during a visual novelty oddball ...

    • Age-related differences in enhancement and suppression of neural activity underlying selective attention in matched young and old adults 

      Haring, A.E.; Zhuravleva, T.Y.; Alperin, B.R.; Rentz, Dorene May; Holcomb, P.J.; Daffner, Kirk R. (Elsevier BV, 2013)
      Selective attention reflects the top-down control of sensory processing that is mediated by enhancement or inhibition of neural activity. ERPs were used to investigate age-related differences in neural activity in an ...

    • Cognitive status impacts age-related changes in attention to novel and target events in normal adults. 

      Daffner, Kirk R.; Chong, Hyemi; Riis, Jenna; Rentz, Dorene May; Wolk, David A.; Budson, Andrew E.; Holcomb, Phillip J. (American Psychological Association (APA), 2007)
      In this study, the authors investigated the relationship between the cognitive status of normal adults and age-related changes in attention to novel and target events. Old, middle-age, and young subjects, divided into ...

    • Compensatory neural activity distinguishes different patterns of normal cognitive aging 

      Riis, Jenna L.; Chong, Hyemi; Ryan, Katherine K.; Wolk, David A.; Rentz, Dorene May; Holcomb, Phillip J.; Daffner, Kirk R. (Elsevier BV, 2008)
      Most cognitive neuroscientific research exploring the nature of age-associated compensatory mechanisms has compared old adults (high vs. average performers) to young adults (not split by performance), leaving ambiguous ...

    • The Dissociation between Early and Late Selection in Older Adults 

      Alperin, Brittany R.; Haring, Anna E.; Zhuravleva, Tatyana; Holcomb, Phillip J.; Rentz, Dorene May; Daffner, Kirk R. (MIT Press - Journals, 2013)
      Older adults exhibit a reduced ability to ignore task-irrelevant stimuli; however, it remains to be determined where along the information processing stream the most salient age-associated changes occur. In the current ...

    • Does compensatory neural activity survive old-old age? 

      Daffner, Kirk R.; Sun, Xue; Tarbi, Elise C.; Rentz, Dorene May; Holcomb, Phillip J.; Riis, Jenna L. (Elsevier BV, 2011)
      One mechanism that may allow older adults to continue to successfully perform certain cognitive tasks is to allocate more resources than their younger counterparts. Most prior studies have not included individuals beyond ...

    • Does modulation of selective attention to features reflect enhancement or suppression of neural activity? 

      Daffner, Kirk R.; Zhuravleva, Tatyana; Sun, Xue; Tarbi, Elise C.; Haring, Anna E.; Rentz, Dorene May; Holcomb, Phillip J. (Elsevier BV, 2012)
      Numerous studies have demonstrated that selective attention to color is associated with a larger neural response under attend than ignore conditions, but have not addressed whether this difference reflects enhanced activity ...

    • Frontal and Parietal Components of a Cerebral Network Mediating Voluntary Attention to Novel Events 

      Daffner, Kirk R.; Scinto, L. F. M.; Weitzman, A. M.; Faust, R.; Rentz, Dorene May; Budson, Andrew E.; Holcomb, P. J. (MIT Press - Journals, 2003)
      Despite the important role that attending to novel events plays in human behavior, there is limited information about the neuroanatomical underpinnings of this vital activity. This study investigated the relative contributions ...

    • Increased Responsiveness to Novelty is Associated with Successful Cognitive Aging 

      Daffner, Kirk R.; Ryan, Katherine K.; Williams, Danielle M.; Budson, Andrew E.; Rentz, Dorene May; Wolk, David A.; Holcomb, Phillip J. (MIT Press - Journals, 2006)
      The animal literature suggests that exposure to more complex, novel environments promotes neurogenesis and cognitive performance in older animals. Studies in humans indicate that participation in intellectually stimulating ...

    • The Influence of Executive Capacity on Selective Attention and Subsequent Processing 

      Daffner, Kirk R.; Tarbi, Elise C.; Haring, Anna E.; Zhuravleva, Tatyana; Sun, Xue; Rentz, Dorene M.; Holcomb, Phillip J. (Frontiers Media S.A., 2012)
      Recent investigations that suggest selective attention (SA) is dependent on top-down control mechanisms lead to the expectation that individuals with high executive capacity (EC) would exhibit more robust neural indices ...

    • Intelligence quotient–adjusted memory impairment is associated with abnormal single photon emission computed tomography perfusion 

      Rentz, Dorene May; Huh, Terri J.; Sardinha, Lisa M.; Moran, Erin K.; Becker, John Alex; Daffner, Kirk R.; Sperling, Reisa Anne; Johnson, Keith Alan (Cambridge University Press (CUP), 2007)
      Cognitive reserve among highly intelligent older individuals makes detection of early Alzheimer's disease (AD) difficult. We tested the hypothesis that mild memory impairment determined by IQ-adjusted norms is associated ...

    • Pathophysiology underlying diminished attention to novel events in patients with early AD 

      Daffner, Kirk R.; Rentz, Dorene May; Scinto, L. F.M.; Faust, R.; Budson, Andrew E.; Holcomb, P. J. (Ovid Technologies (Wolters Kluwer Health), 2001)
      Background: Patients with mild to moderate AD often are apathetic and fail to attend to novel aspects of their environment. Objective: To investigate the mechanisms underlying these changes by studying the novelty P3 ...

    • A Potential Noninvasive Neurobiological Test for Alzheimer's Disease 

      Scinto, L.; Daffner, Kirk R.; Dressler, D; Ransil, B.; Rentz, Dorene; Weintraub, S; Mesulam, M; Potter, H (American Association for the Advancement of Science (AAAS), 1994)
      Currently Alzheimer's disease, which affects more than 20 million people worldwide, can only be definitely diagnosed by histological examination of brain tissue obtained at autopsy or biopsy. There is a great need for an ...

    • Promising developments in neuropsychological approaches for the detection of preclinical Alzheimer’s disease: a selective review 

      Rentz, Dorene M; Parra Rodriguez, Mario A; Amariglio, Rebecca; Stern, Yaakov; Sperling, Reisa; Ferris, Steven (BioMed Central, 2013)
      Recently published guidelines suggest that the most opportune time to treat individuals with Alzheimer’s disease is during the preclinical phase of the disease. This is a phase when individuals are defined as clinically ...

    • Use of IQ-Adjusted Norms to Predict Progressive Cognitive Decline in Highly Intelligent Older Individuals 

      Huh, Terri J.; Faust, Robert R.; Sperling, Reisa Anne; Daffner, Kirk R.; Rentz, Dorene; Budson, Andrew; Scinto, Leonard; Sperling, Reisa Anne (American Psychological Association (APA), 2004-01)
      Identifying high-functioning older individuals in preclinical phases of Alzheimer's disease (AD) may require more sensitive methods than the standard approach. The authors explored the utility of adjusting for premorbid ...