Now showing items 1-13 of 13

    • Aspirin Use and Risk of Atrial Fibrillation in the Physicians' Health Study 

      Ofman, Peter; Petrone, Andrew B.; Peralta, Adelqui; Hoffmeister, Peter; Albert, Christine M.; Djousse, Luc; Gaziano, J. Michael; Rahilly‐Tierney, Catherine R. (Blackwell Publishing Ltd, 2014)
      Background: Inflammatory processes have been associated with an increased risk of atrial fibrillation (AF), potentially allowing for preventive therapy by anti‐inflammatory agents such as aspirin. However, the effect of ...
    • Association of Lipid-Related Genetic Variants with the Incidence of Atrial Fibrillation: The AFGen Consortium 

      Norby, Faye L.; Eryd, Samuel Adamsson; Niemeijer, Maartje N.; Rose, Lynda M.; Smith, Albert V.; Yin, Xiaoyan; Agarwal, Sunil K.; Arking, Dan E.; Chasman, Daniel L.; Chen, Lin Y.; Eijgelsheim, Mark; Engström, Gunnar; Franco, Oscar H.; Heeringa, Jan; Hindy, George; Hofman, Albert; Lutsey, Pamela L.; Magnani, Jared W.; McManus, David D.; Orho-Melander, Marju; Pankow, James S.; Rukh, Gull; Schulz, Christina-Alexandra; Uitterlinden, André G.; Albert, Christine M.; Benjamin, Emelia J.; Gudnason, Vilmundur; Smith, J. Gustav; Stricker, Bruno H. C.; Alonso, Alvaro (Public Library of Science, 2016)
      Background: Several studies have shown associations between blood lipid levels and the risk of atrial fibrillation (AF). To test the potential effect of blood lipids with AF risk, we assessed whether previously developed ...
    • Dietary and Plasma Magnesium and Risk of Coronary Heart Disease Among Women 

      Chiuve, Stephanie Elizabeth; Sun, Qi; Curhan, Gary Craig; Taylor, Eric N.; Spiegelman, Donna Lynn; Willett, Walter C.; Manson, JoAnn Elisabeth; Rexrode, Kathryn Marian; Albert, Christine Marie (Blackwell Publishing Ltd, 2013)
      Background: Magnesium is associated with lower risk of sudden cardiac death, possibly through antiarrhythmic mechanisms. Magnesium influences endothelial function, inflammation, blood pressure, and diabetes, but a direct ...
    • Effect Modification of Long‐Term Air Pollution Exposures and the Risk of Incident Cardiovascular Disease in US Women 

      Hart, Jaime E.; Puett, Robin C.; Rexrode, Kathryn M.; Albert, Christine M.; Laden, Francine (John Wiley and Sons Inc., 2015)
      Background: Ambient air pollution exposures have been frequently linked to cardiovascular disease (CVD) morbidity and mortality. However, less is known about the populations most susceptible to these adverse effects. Methods ...
    • Effect of Homocysteine-Lowering Treatment With Folic Acid and B Vitamins on Risk of Type 2 Diabetes in Women 

      Song, Yiqing; Cook, Nancy Romanowicz; Albert, Christine Marie; Van Denburgh, Martin; Manson, JoAnn Elisabeth (American Diabetes Association, 2009)
      OBJECTIVE: Homocysteinemia may play an etiologic role in the pathogenesis of type 2 diabetes by promoting oxidative stress, systemic inflammation, and endothelial dysfunction. We investigated whether homocysteine-lowering ...
    • Gene-gene Interaction Analyses for Atrial Fibrillation 

      Lin, Honghuang; Mueller-Nurasyid, Martina; Smith, Albert V.; Arking, Dan E.; Barnard, John; Bartz, Traci M.; Lunetta, Kathryn L.; Lohman, Kurt; Kleber, Marcus E.; Lubitz, Steven A.; Geelhoed, Bastiaan; Trompet, Stella; Niemeijer, Maartje N.; Kacprowski, Tim; Chasman, Daniel I.; Klarin, Derek; Sinner, Moritz F.; Waldenberger, Melanie; Meitinger, Thomas; Harris, Tamara B.; Launer, Lenore J.; Soliman, Elsayed Z.; Chen, Lin Y.; Smith, Jonathan D.; Van Wagoner, David R.; Rotter, Jerome I.; Psaty, Bruce M.; Xie, Zhijun; Hendricks, Audrey E.; Ding, Jingzhong; Delgado, Graciela E.; Verweij, Niek; van der Harst, Pim; Macfarlane, Peter W.; Ford, Ian; Hofman, Albert; Uitterlinden, André; Heeringa, Jan; Franco, Oscar H.; Kors, Jan A.; Weiss, Stefan; Völzke, Henry; Rose, Lynda M.; Natarajan, Pradeep; Kathiresan, Sekar; Kääb, Stefan; Gudnason, Vilmundur; Alonso, Alvaro; Chung, Mina K.; Heckbert, Susan R.; Benjamin, Emelia J.; Liu, Yongmei; März, Winfried; Rienstra, Michiel; Jukema, J. Wouter; Stricker, Bruno H.; Dörr, Marcus; Albert, Christine M.; Ellinor, Patrick T. (Nature Publishing Group, 2016)
      Atrial fibrillation (AF) is a heritable disease that affects more than thirty million individuals worldwide. Extensive efforts have been devoted to the study of genetic determinants of AF. The objective of our study is to ...
    • Incidence and Risk Factors of Ventricular Fibrillation Before Primary Angioplasty in Patients With First ST‐Elevation Myocardial Infarction: A Nationwide Study in Denmark 

      Jabbari, Reza; Engstrøm, Thomas; Glinge, Charlotte; Risgaard, Bjarke; Jabbari, Javad; Winkel, Bo Gregers; Terkelsen, Christian Juhl; Tilsted, Hans‐Henrik; Jensen, Lisette Okkels; Hougaard, Mikkel; Chiuve, Stephanie E.; Pedersen, Frants; Svendsen, Jesper Hastrup; Haunsø, Stig; Albert, Christine M.; Tfelt‐Hansen, Jacob (Blackwell Publishing Ltd, 2014)
      Background: We aimed to investigate the incidence and risk factors for ventricular fibrillation (VF) before primary percutaneous coronary intervention (PPCI) among patients with ST‐segment elevation myocardial infarction ...
    • Lifestyle‐Based Prediction Model for the Prevention of CVD: The Healthy Heart Score 

      Chiuve, Stephanie E.; Cook, Nancy R.; Shay, Christina M.; Rexrode, Kathryn M.; Albert, Christine M.; Manson, JoAnn E.; Willett, Walter C.; Rimm, Eric B. (Blackwell Publishing Ltd, 2014)
      Background: Clinical practice focuses on the primary prevention of cardiovascular (CV) disease (CVD) through the modification and pharmacological treatment of elevated risk factors. Prediction models based on established ...
    • Novel genetic markers improve measures of atrial fibrillation risk prediction 

      Everett, Brendan M.; Cook, Nancy R.; Conen, David; Chasman, Daniel I.; Ridker, Paul M; Albert, Christine M. (Oxford University Press, 2013)
      Aims Atrial fibrillation (AF) is associated with adverse outcome. Whether recently discovered genetic risk markers improve AF risk prediction is unknown. Methods and results We derived and validated a novel AF risk prediction ...
    • Novel Loci Associated with Increased Risk of Sudden Cardiac Death in the Context of Coronary Artery Disease 

      Huertas-Vazquez, Adriana; Nelson, Christopher P.; Guo, Xiuqing; Reinier, Kyndaron; Uy-Evanado, Audrey; Teodorescu, Carmen; Ayala, Jo; Jerger, Katherine; Chugh, Harpriya; WTCCC+; Braund, Peter S.; Deloukas, Panos; Hall, Alistair S.; Balmforth, Anthony J.; Jones, Michelle; Taylor, Kent D.; Pulit, Sara L.; Newton-Cheh, Christopher Holmes; Gunson, Karen; Jui, Jonathan; Rotter, Jerome I.; Albert, Christine Marie; Samani, Nilesh J.; Chugh, Sumeet S. (Public Library of Science, 2013)
      Background: Recent genome-wide association studies (GWAS) have identified novel loci associated with sudden cardiac death (SCD). Despite this progress, identified DNA variants account for a relatively small portion of ...
    • Obesity, Physical Activity, and Their Interaction in Incident Atrial Fibrillation in Postmenopausal Women 

      Azarbal, Farnaz; Stefanick, Marcia L.; Salmoirago‐Blotcher, Elena; Manson, JoAnn E.; Albert, Christine M.; LaMonte, Michael J.; Larson, Joseph C.; Li, Wenjun; Martin, Lisa W.; Nassir, Rami; Garcia, Lorena; Assimes, Themistocles L.; Tharp, Katie M.; Hlatky, Mark A.; Perez, Marco V. (Blackwell Publishing Ltd, 2014)
      Background: Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with increased risk of stroke and death. Obesity is an independent risk factor for AF, but modifiers of this risk are not well ...
    • Plasma Levels of Fetuin‐A and Risk of Coronary Heart Disease in US Women: The Nurses' Health Study 

      Sun, Qi; Jiménez, Monik C.; Townsend, Mary K.; Rimm, Eric B.; Manson, JoAnn E.; Albert, Christine M.; Rexrode, Kathryn M. (Blackwell Publishing Ltd, 2014)
      Background: Fetuin‐A may be involved in the etiology of coronary heart disease (CHD) through opposing pathways (ie, promoting insulin resistance and inhibiting ectopic calcification). We aimed to explicitly examine whether ...
    • Predisposing Factors Associated With Development of Persistent Compared With Paroxysmal Atrial Fibrillation 

      Sandhu, Roopinder K.; Conen, David; Tedrow, Usha B.; Fitzgerald, Kathryn C.; Pradhan, Aruna D.; Ridker, Paul M; Glynn, Robert J.; Albert, Christine M. (Blackwell Publishing Ltd, 2014)
      Background: Once atrial fibrillation (AF) progresses to sustained forms, adverse outcomes increase and treatment success rates decrease. Therefore, identification of risk factors predisposing to persistence of AF may have ...