Browsing by Author "Tsai, Alexander"
Now showing items 1-20 of 23
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Adjunctive Atypical Antipsychotic Treatment for Major Depressive Disorder: A Meta-Analysis of Depression, Quality of Life, and Safety Outcomes
Spielmans, Glen I.; Berman, Margit I.; Linardatos, Eftihia; Rosenlicht, Nicholas Z.; Perry, Angela; Tsai, Alexander Chung-Yu (Public Library of Science, 2013)Background: Atypical antipsychotic medications are widely prescribed for the adjunctive treatment of depression, yet their total risk–benefit profile is not well understood. We thus conducted a systematic review of the ... -
Aripiprazole in the Maintenance Treatment of Bipolar Disorder: A Critical Review of the Evidence and Its Dissemination into the Scientific Literature
Tsai, Alexander C.; Rosenlicht, Nicholas Z.; Jureidini, Jon N.; Parry, Peter I.; Spielmans, Glen I.; Healy, David (Public Library of Science, 2011)Background: Aripiprazole, a second-generation antipsychotic medication, has been increasingly used in the maintenance treatment of bipolar disorder and received approval from the U.S. Food and Drug Administration for this ... -
Comparative Effectiveness of Induction Therapy for Human Immunodeficiency Virus-Associated Cryptococcal Meningitis: A Network Meta-Analysis
Campbell, Jeffrey I.; Kanters, Steve; Bennett, John E.; Thorlund, Kristian; Tsai, Alexander C.; Mills, Edward J.; Siedner, Mark J. (Oxford University Press, 2015)Background. Multiple international treatment guidelines recommend amphotericin-based combination regimens for induction therapy of cryptococcal meningitis. Yet, only 1 trial has reported a mortality benefit for combination ... -
Depression During Pregnancy and the Postpartum Among HIV-Infected Women on Antiretroviral Therapy in Uganda
Kaida, Angela; Matthews, Lynn T.; Ashaba, Scholastic; Tsai, Alexander C.; Kanters, Steve; Robak, Magdalena; Psaros, Christina; Kabakyenga, Jerome; Boum, Yap; Haberer, Jessica E.; Martin, Jeffrey N.; Hunt, Peter W.; Bangsberg, David R. (JAIDS Journal of Acquired Immune Deficiency Syndromes, 2014)Background: Among HIV-infected women, perinatal depression compromises clinical, maternal, and child health outcomes. Antiretroviral therapy (ART) is associated with lower depression symptom severity but the uniformity of ... -
Dissemination of Research Findings to Research Participants Living with HIV in Rural Uganda: Challenges and Rewards
Baylor, Anna; Muzoora, Conrad; Bwana, Mwebsa; Kembabazi, Annet; Haberer, Jessica; Matthews, Lynn Turner; Tsai, Alexander Chung-Yu; Hunt, Peter K.; Martin, Jeffrey N.; Bangsberg, David Roy (Public Library of Science, 2013)David Bangsberg and colleagues explore the challenges and rewards of sharing research findings with participants living with HIV enrolled in observational research in rural sub-Saharan Africa. -
Empiric Deworming and CD4 Count Recovery in HIV-Infected Ugandans Initiating Antiretroviral Therapy
Lankowski, Alexander J.; Tsai, Alexander C.; Kanyesigye, Michael; Bwana, Mwebesa; Haberer, Jessica E.; Wenger, Megan; Martin, Jeffrey N.; Bangsberg, David R.; Hunt, Peter W.; Siedner, Mark J. (Public Library of Science, 2014)Background: There is conflicting evidence on the immunologic benefit of treating helminth co-infections (“deworming”) in HIV-infected individuals. Several studies have documented reduced viral load and increased CD4 count ... -
Harnessing Poverty Alleviation to Reduce the Stigma of HIV in Sub-Saharan Africa
Tsai, Alexander C.; Bangsberg, David R.; Weiser, Sheri D. (Public Library of Science, 2013)Alexander Tsai and colleagues highlight the complex relationship between poverty and HIV stigma in sub-Saharan Africa, and discuss possible ways to break the cycle. Please see later in the article for the Editors' Summary -
Home Foreclosure, Health, and Mental Health: A Systematic Review of Individual, Aggregate, and Contextual Associations
Tsai, Alexander C. (Public Library of Science, 2015)Background: The U.S. foreclosure crisis intensified markedly during the Great Recession of 2007-09, and currently an estimated five percent of U.S. residential properties are more than 90 days past due or in the process ... -
Household malaria knowledge and its association with bednet ownership in settings without large–scale distribution programs: Evidence from rural Madagascar
Krezanoski, Paul J.; Tsai, Alexander C.; Hamer, Davidson H.; Comfort, Alison B.; Bangsberg, David R. (Edinburgh University Global Health Society, 2014)Background: Insecticide–treated bednets are effective at preventing malaria. This study focuses on household–level factors that are associated with bednet ownership in a rural area of Madagascar which had not been a recipient ... -
Impact of HIV-related stigma on treatment adherence: systematic review and meta-synthesis
Katz, Ingrid T; Ryu, Annemarie E; Onuegbu, Afiachukwu G; Psaros, Christina; Weiser, Sheri D; Bangsberg, David R; Tsai, Alexander C (International AIDS Society, 2013)Introduction: Adherence to HIV antiretroviral therapy (ART) is a critical determinant of HIV-1 RNA viral suppression and health outcomes. It is generally accepted that HIV-related stigma is correlated with factors that may ... -
Inequitable and Ineffective: Exclusion of Mental Health from the Post-2015 Development Agenda
Tsai, Alexander C.; Tomlinson, Mark (Public Library of Science, 2015)Alex Tsai and Mark Tomlinson argue for a place for mental health on the post-2015 development agenda. -
Intimate partner violence and HIV: embracing complexity
Harling, Guy Duncan; Tsai, Alexander Chung-Yu; Subramanian, S.V. Venkata (Elsevier BV, 2015)Dick Durevall and Annika Lindskog (January, 2015) explore the association between intimate partner violence (IPV) and HIV infection in Demographic and Health Survey (DHS) data.1 We welcome Durevall and Lindskog's examination ... -
Intimate Partner Violence and Population Mental Health: Why Poverty and Gender Inequities Matter
Tsai, Alexander Chung-Yu (Public Library of Science, 2013)Alexander Tsai discusses a new research study by Karen Devries and colleagues, and comments on the possible impact on public health of the study's insights regarding the relationship between intimate partner violence and ... -
Medical Evidence of Human Rights Violations against Non-Arabic-Speaking Civilians in Darfur: A Cross-Sectional Study
Tsai, Alexander Chung-Yu; Eisa, Mohammed A.; Crosby, Sondra S.; Sirkin, Susannah; Heisler, Michele; Leaning, Jennifer; Iacopino, Vincent (Public Library of Science, 2012)Background: Ongoing conflict in the Darfur region of Sudan has resulted in a severe humanitarian crisis. We sought to characterize the nature and geographic scope of allegations of human rights violations perpetrated against ... -
Mental health spillovers and the Millennium Development Goals: The case of perinatal depression in Khayelitsha, South Africa
Tsai, Alexander C.; Tomlinson, Mark (Edinburgh University Global Health Society, 2012) -
The Missing Men: HIV Treatment Scale-Up and Life Expectancy in Sub-Saharan Africa
Tsai, Alexander C.; Siedner, Mark J. (Public Library of Science, 2015)In a Perspective accompanying Bor and colleagues, Alexander Tsai and Mark Siedner discuss the gender gap in ART uptake and HIV mortality in Africa. -
Personal contact with HIV-positive persons is associated with reduced HIV stigma: cross-sectional analysis of general population surveys from 26 countries in sub-Saharan Africa
Chan, Brian Tan; Tsai, Alexander Chung-Yu (International AIDS Socity, 2016)Introduction: HIV-related stigma hampers treatment and prevention efforts worldwide. Effective interventions to counter HIV-related stigma are greatly needed. Although the “contact hypothesis” suggests that personal contact ... -
A Qualitative Analysis of Factors Influencing HPV Vaccine Uptake in Soweto, South Africa among Adolescents and Their Caregivers
Katz, Ingrid T.; Nkala, Busisiwe; Dietrich, Janan; Wallace, Melissa; Bekker, Linda-Gail; Pollenz, Kathryn; Bogart, Laura M.; Wright, Alexi A.; Tsai, Alexander C.; Bangsberg, David R.; Gray, Glenda E. (Public Library of Science, 2013)Background: In South Africa, the prevalence of oncogenic Human Papillomavirus (HPV) may be as high as 64%, and cervical cancer is the leading cause of cancer-related death among women. The development of efficacious ... -
Reliability and Validity of Instruments for Assessing Perinatal Depression in African Settings: Systematic Review and Meta-Analysis
Tsai, Alexander C.; Scott, Jennifer A.; Hung, Kristin J.; Zhu, Jennifer Q.; Matthews, Lynn T.; Psaros, Christina; Tomlinson, Mark (Public Library of Science, 2013)Background: A major barrier to improving perinatal mental health in Africa is the lack of locally validated tools for identifying probable cases of perinatal depression or for measuring changes in depression symptom severity. ... -
Rethinking the “Pre” in Pre-Therapy Counseling: No Benefit of Additional Visits Prior to Therapy on Adherence or Viremia in Ugandans Initiating ARVs
Lankowski, Alexander; Kembabazi, Annet; Emenyonu, Nneka; Muzoora, Conrad; Geng, Elvin; Martin, Jeffrey N.; Siedner, Mark Jacob; Haberer; Haberer, Jessica; Tsai, Alexander Chung-Yu; Bangsberg, David Roy (Public Library of Science, 2012)Background: Many guidelines recommend adherence counseling prior to initiating antiretrovirals (ARVs), however the additional benefit of pre-therapy counseling visits on early adherence is not known. We sought to assess ...