Browsing by Author "Spiegelman, Donna"
Now showing items 1-20 of 60
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Abuse in Childhood and Adolescence As a Predictor of Type 2 Diabetes in Adult Women
Rich-Edwards, Janet Wilson; Spiegelman, Donna Lynn; Lividoti Hibert, Eileen; Jun, Hee-Jin; Todd, Tamarra James; Kawachi, Ichiro; Wright, Rosalind (Elsevier BV, 2010)Background: Although child abuse is associated with obesity, it is not known whether early abuse increases risk of type 2 diabetes. Purpose: To investigate associations of child and adolescent abuse with adult diabetes. ... -
Adverse Outcomes of Underuse of β-Blockers in Elderly Survivors of Acute Myocardial Infarction
Soumerai, Stephen Bertram; McLaughlin, Thomas J.; Spiegelman, Donna Lynn; Hertzmark, Ellen; Thibault, George Edwin; Goldman, Lee (American Medical Association (AMA), 1997)Objectives. —To study determinants and adverse outcomes (mortality and rehospitalization) of β-blocker underuse in elderly patients with myocardial infarction; and whether the relative risks (RRs) of survival associated ... -
Anaemia, prenatal iron use, and risk of adverse pregnancy outcomes: systematic review and meta-analysis
Haider, Batool A; Olofin, Ibironke; Wang, Molin; Spiegelman, Donna; Ezzati, Majid; Fawzi, Wafaie W (BMJ Publishing Group Ltd., 2013)Objectives: To summarise evidence on the associations of maternal anaemia and prenatal iron use with maternal haematological and adverse pregnancy outcomes; and to evaluate potential exposure-response relations of dose of ... -
Anemia at the Initiation of Tuberculosis Therapy Is Associated with Delayed Sputum Conversion among Pulmonary Tuberculosis Patients in Dar-es-Salaam, Tanzania
Nagu, Tumaini J.; Spiegelman, Donna; Hertzmark, Ellen; Aboud, Said; Makani, Julie; Matee, Mecky I.; Fawzi, Wafaie; Mugusi, Ferdinand (Public Library of Science, 2014)Background: Pulmonary tuberculosis and anemia are both prevalent in Tanzania. There is limited and inconsistent literature on the association between anemia and sputum conversion following tuberculosis treatment. Methods: ... -
Anemia Etiology in Ethiopia: Assessment of Nutritional, Infectious Disease, and Other Risk Factors in a Population-based Cross-sectional Survey of Women, Men, and Children
Andersen, Christopher; Tadesse, Amare; Bromage, Sabri; Fekadu, Habtamu; Hemler, Elena; Passarelli, Simone; Spiegelman, Donna; Sudfeld, Christopher; Worku, Alemayehu; Berhane, Yemane; Fawzi, Wafaie (Oxford University Press (OUP), 2021-10-14)Background: While the causes of anemia at an individual level (such as certain nutritional deficiencies, infections, and genetic disorders) are well defined, there is limited understanding of the relative burden of anemia ... -
Associations of Plasma Phospholipid and Dietary Alpha Linolenic Acid With Incident Atrial Fibrillation in Older Adults: The Cardiovascular Health Study
Fretts, Amanda M.; Mozaffarian, Dariush; Siscovick, David S.; Heckbert, Susan R.; McKnight, Barbara; King, Irena B.; Rimm, Eric B.; Psaty, Bruce M.; Sacks, Frank Martin; Song, Xiaoling; Spiegelman, Donna Lynn; Lemaitre, Rozenn N. (Blackwell Publishing Ltd, 2013)Background: Few studies have examined the relationship of α‐linolenic acid (ALA 18:3n‐3), an intermediate‐chain essential n‐3 polyunsaturated fatty acid derived from plants and vegetable oils, with incident atrial fibrillation ... -
Cervical cancer risk factors among HIV-infected Nigerian women
Ononogbu, Uzoma; Almujtaba, Maryam; Modibbo, Fatima; Lawal, Ishak; Offiong, Richard; Olaniyan, Olayinka; Dakum, Patrick; Spiegelman, Donna; Blattner, William; Adebamowo, Clement (BioMed Central, 2013)Background: Cervical cancer is the third most common cancer among women worldwide, and in Nigeria it is the second most common female cancer. Cervical cancer is an AIDS-defining cancer; however, HIV only marginally increases ... -
Circulating Long-Chain ?-3 Fatty Acids and Incidence of Congestive Heart Failure in Older Adults: The Cardiovascular Health Study
Mozaffarian, Dariush; Lemaitre, Rozenn N.; King, Irena B.; Song, Xiaoling; Spiegelman, Donna Lynn; Sacks, Frank Martin; Rimm, Eric Bruce; Siscovick, David S. (American College of Physicians, 2011)BACKGROUND: Few previous studies have evaluated associations between long-chain ω-3 fatty acids and incidence of congestive heart failure (CHF), and those that have are typically based on diet questionnaires and yield ... -
Circulating Omega‐3 Polyunsaturated Fatty Acids and Subclinical Brain Abnormalities on MRI in Older Adults: The Cardiovascular Health Study
Virtanen, Jyrki K.; Siscovick, David S.; Lemaitre, Rozenn N.; Longstreth, William T.; Spiegelman, Donna; Rimm, Eric B.; King, Irena B.; Mozaffarian, Dariush (Blackwell Publishing Ltd, 2013)Background: Consumption of tuna or other broiled or baked fish, but not fried fish, is associated with fewer subclinical brain abnormalities on magnetic resonance imaging (MRI). We investigated the association between ... -
Combined impact of lifestyle factors on mortality: prospective cohort study in US women
van Dam, Rob M.; Li, Tricia; Spiegelman, Donna Lynn; Franco, Oscar H; Hu, Frank B. (BMJ Publishing Group Ltd., 2008)Objective: To evaluate the impact of combinations of lifestyle factors on mortality in middle aged women. Design: Prospective cohort study. Setting: Nurses’ health study, United States. Participants: 77 782 women aged 34 ... -
Common ataxia telangiectasia mutated haplotypes and risk of breast cancer: a nested case–control study
Tamimi, Rulla May; Hankinson, Susan Elizabeth; Spiegelman, Donna Lynn; Kraft, Peter; Colditz, Graham A.; Hunter, David J. (BioMed Central, 2004)Introduction: The ataxia telangiectasia mutated (ATM) gene is a tumor suppressor gene with functions in cell cycle arrest, apoptosis, and repair of DNA double-strand breaks. Based on family studies, women heterozygous for ... -
Consumption and acceptability of whole grain staples for lowering markers of diabetes risk among overweight and obese Tanzanian adults
Muhihi, Alfa; Gimbi, Dorothy; Njelekela, Marina; Shemaghembe, Emmanuel; Mwambene, Kissah; Chiwanga, Faraja; Malik, Vasanti S; Wedick, Nicole M; Spiegelman, Donna; Hu, Frank B; Willett, Walter C (BioMed Central, 2013)Background: Dietary changes characterized by a reduction in carbohydrate quality are occurring in developing countries and may be associated with a higher prevalence of obesity and chronic diseases such as type 2 diabetes ... -
Determinants of Anemia in Postpartum HIV-Negative Women in Dar es Salaam, Tanzania
Petraro, Paul; Duggan, Christopher Paul; Urassa, Willy; Msamanga, Gernard; Makubi, Abel; Spiegelman, Donna Lynn; Fawzi, Wafaie W. (Nature Publishing Group, 2013)Objective: The determinants of anemia during both pregnancy and postpartum recovery remain incompletely understood in sub-Saharan African women. Subjects/methods: In a prospective cohort study among pregnant women, we ... -
Dietary and Plasma Magnesium and Risk of Coronary Heart Disease Among Women
Chiuve, Stephanie Elizabeth; Sun, Qi; Curhan, Gary Craig; Taylor, Eric N.; Spiegelman, Donna Lynn; Willett, Walter C.; Manson, JoAnn Elisabeth; Rexrode, Kathryn Marian; Albert, Christine Marie (Blackwell Publishing Ltd, 2013)Background: Magnesium is associated with lower risk of sudden cardiac death, possibly through antiarrhythmic mechanisms. Magnesium influences endothelial function, inflammation, blood pressure, and diabetes, but a direct ... -
Dyslipidemia in an HIV-Positive Antiretroviral Treatment-Naive Population in Dar es Salaam, Tanzania
Armstrong, Catharina; Liu, Enju; Okuma, James; Spiegelman, Donna Lynn; Guerino, Chalamilla; Njelekela, Marina Alois; Grinspoon, Steven Kyle; Fawzi, Wafaie W.; Hawkins, Claudia (Ovid Technologies (Wolters Kluwer Health), 2011)Limited data are available on dyslipidemia in HIV-infected patients in resource-limited settings (RLS). We performed a cross-sectional analysis in ART-naïve, non-fasting HIV-infected patients in Tanzania between November ... -
Effect of High-Dose vs Standard-Dose Multivitamin Supplementation at the Initiation of HAART on HIV Disease Progression and Mortality in Tanzania
Isanaka, Sheila; Mugusi, Ferdinand; Hawkins, Claudia; Spiegelman, Donna Lynn; Okuma, James; Aboud, Said; Guerino, Chalamilla; Fawzi, Wafaie W. (American Medical Association (AMA), 2012)Context Large randomized trials have previously shown that high-dose micronutrient supplementation can increase CD4 counts and reduce human immunodeficiency virus (HIV) disease progression and mortality among individuals ... -
Effect of multivitamin supplements on weight gain during pregnancy among HIV-negative women in Tanzania
Changamire, Freeman T.; Mwiru, Ramadhani S.; Peterson, Karen E.; Msamanga, Gernard I.; Spiegelman, Donna Lynn; Petraro, Paul; Urassa, Willy; Fawzi, Wafaie W. (Wiley-Blackwell, 2012)Multivitamin supplementation has been shown to reduce the risk of low birthweight. This effect could be mediated through gestational weight gain. However, the effect of multivitamin supplementation on weight gain during ... -
Effect of Selenium Supplements on Hemoglobin Concentration and Morbidity among HIV‐1–Infected Tanzanian Women
Kupka, Roland; Mugusi, Ferdinand; Aboud, Said; Hertzmark, Ellen; Spiegelman, Donna Lynn; Fawzi, Wafaie W. (Oxford University Press (OUP), 2009)Selenium deficiency may increase risks of anemia and morbidity among people with human immunodeficiency virus infection. We therefore investigated the effect of selenium supplements (200 µg of selenomethionine) on these ... -
Effectiveness of a multivitamin supplementation program among HIV-infected adults in Tanzania
Sudfeld, Christopher R.; Buchanan, Ashley; Ulenga, Nzovu; Spiegelman, Donna; Mtisi, Expeditho; Hertzmark, Ellen; Muya, Aisa N.; Sando, David; Mungure, Ester; Fawzi, Wafaie; Mizinduko, Mucho (Ovid Technologies (Wolters Kluwer Health), 2018-10)Abstract Objective: The objective of this study was to assess the effectiveness of a routine multivitamin supplementation program for adults living with HIV in Tanzania. Design: We conducted a retrospective cohort study ... -
Exposure measurement error in PM2.5 health effects studies: A pooled analysis of eight personal exposure validation studies
Kioumourtzoglou, Marianthi-Anna; Spiegelman, Donna; Szpiro, Adam A; Sheppard, Lianne; Kaufman, Joel D; Yanosky, Jeff D; Williams, Ronald; Laden, Francine; Hong, Biling; Suh, Helen (BioMed Central, 2014)Background: Exposure measurement error is a concern in long-term PM2.5 health studies using ambient concentrations as exposures. We assessed error magnitude by estimating calibration coefficients as the association between ...