Now showing items 1-5 of 5

    • Alternative Methods for Characterization of Extracellular Vesicles 

      Balaj, Leonora; Tigges, John; Toxavidis, Vasilis; Ivanov, Alexander R.; Skog, Johan; Momen Heravi, Fatemeh; Alian, Sara; Ericsson, Maria; Distel, Robert; Kuo, Winston Patrick (Frontiers Research Foundation, 2012)
      Extracellular vesicles (ECVs) are nano-sized vesicles released by all cells in vitro as well as in vivo. Their role has been implicated mainly in cell–cell communication, but also in disease biomarkers and more recently ...
    • Impact of Biofluid Viscosity on Size and Sedimentation Efficiency of the Isolated Microvesicles 

      Momen-Heravi, Fatemeh; Balaj, Leonora; Alian, Sara; Trachtenberg, Alexander J.; Hochberg, Fred Harvey; Skog, Johan; Kuo, Winston Patrick (Frontiers Research Foundation, 2012)
      Microvesicles are nano-sized lipid vesicles released by all cells in vivo and in vitro. They are released physiologically under normal conditions but their rate of release is higher under pathological conditions such as ...
    • MicroSAGE is Highly Representative and Reproducible but Reveals Major Differences in Gene Expression Among Samples Obtained from Similar Tissues 

      Blackshaw, Seth; Kuo, Winston Patrick; Park, Peter J.; Tsujikawa, Motokazu; Gunnersen, Jenny M; Scott, Hamish S; Boon, Wee-Ming; Tan, Seong-Seng; Cepko, Constance L. (BioMed Central, 2003)
      Background: Serial analysis of gene expression using small amounts of starting material (microSAGE) has not yet been conclusively shown to be representative, reproducible or accurate. Results: We show that microSAGE is ...
    • Peripheral Arterial Occlusive Disease: Global Gene Expression Analyses Suggest a Major Role for Immune and Inflammatory Responses 

      Crawford, Keith; Jin, Jason Gang; Du, Yanzhi; Abzhanov, Arkhat; Zhou, Jianqin; Zhang, Ji; Jiang, Mier; Ohno-Machado, Lucila; Fu, Shijun; Zhao, Haiguang; Shi, Jiantao; Kuo, Winston (BioMed Central, 2008)
      Background Peripheral arterial disease (PAD), a major manifestation of atherosclerosis, is associated with significant cardiovascular morbidity, limb loss and death. However, mechanisms underlying the genesis and progression ...
    • Validation of Oligoarrays for Quantitative Exploration of the Transcriptome 

      Nygaard, Vigdis; Holden, Marit; Trimarchi, Jeff; Ohno-Machado, Lucila; Frigessi, Arnoldo; Glad, Ingrid K; Wiel, Mark A van de; Hovig, Eivind; Lyng, Heidi; Liu, Fang; Kuo, Winston Patrick; Cepko, Connie (BioMed Central, 2008)
      Background: Oligoarrays have become an accessible technique for exploring the transcriptome, but it is presently unclear how absolute transcript data from this technique compare to the data achieved with tag-based quantitative ...