Browsing by Author "Altshul, Larisa"
Now showing items 1-20 of 21
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3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) and mutagenic activity in Massachusetts drinking water.
Wright, J Michael; Schwartz, Joel David; Vartiainen, Terttu; Mäki-Paakkanen, Jorma; Altshul, Larisa M.; Harrington, Joseph J; Dockery, Douglas W. (2002)There is limited information on the prevalence of the potent mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in U.S. water supplies. We measured MX concentrations and mutagenic activity in tap water samples ... -
Comparison of Polychlorinated Biphenyl Levels across Studies of Human Neurodevelopment
Longnecker, Matthew P.; Wolff, Mary S.; Gladen, Beth C.; Brock, John W.; Grandjean, Philippe; Jacobson, Joseph L.; Korrick, Susan Abigail; Rogan, Walter J.; Weisglas-Kuperus, Nynke; Hertz-Picciotto, Irva; Ayotte, Pierre; Stewart, Paul; Winneke, Gerhard; Charles, M. Judith; Jacobson, Sandra W.; Dewailly, Éric; Boersma, E. Rudy; Altshul, Larisa M.; Heinzow, Birger; Pagano, James J.; Jensen, Allan A. (Environmental Health Perspectives, 2002)Polychlorinated biphenyls (PCBs) are persistent pollutants that are ubiquitous in the food chain, and detectable amounts are in the blood of almost every person in most populations that have been examined. Extensive evidence ... -
Environmental Exposure to Polychlorinated Biphenyls and p,p´-DDE and Sperm Sex-Chromosome Disomy
McAuliffe, Megan E.; Williams, Paige L.; Korrick, Susan Abigail; Altshul, Larisa M.; Perry, Melissa J. (National Institute of Environmental Health Sciences, 2012)Background: Chromosomal abnormalities contribute substantially to reproductive problems, but the role of environmental risk factors has received little attention. Objectives: We evaluated the association of polychlorinated ... -
Environmental Organochlorines and Semen Quality: Results of a Pilot Study
Hauser, Russ B.; Altshul, Larisa M.; Chen, Zuying; Ryan, Louise Marie; Overstreet, James; Schiff, Isaac; Christiani, David C. (National Institute of Environmental Health Sciences, 2002)There have been numerous studies that suggest that sperm concentrations (sperm counts) are declining in men. However, other studies suggest that sperm counts are not declining or may be increasing in some areas. Although ... -
Evidence of Interaction Between Polychlorinated Biphenyls and Phthalates in Relation to Human Sperm Motility
Hauser, Russ B.; Williams, Paige L.; Altshul, Larisa M.; Calafat, Antonia M. (National Institute of Environmental Health Sciences, 2005)Previously, we reported evidence of inverse associations between exposure to some polychlorinated biphenyls (PCBs) and some phthalate monoesters in relation to semen parameters, specifically sperm motility. Because humans ... -
Genetic Modification of the Association between Peripubertal Dioxin Exposure and Pubertal Onset in a Cohort of Russian Boys
Humblet, Olivier; Korrick, Susan Abigail; Williams, Paige L.; Sergeyev, Oleg; Emond, Claude; Birnbaum, Linda S.; Burns, Jane S; Altshul, Larisa M.; Patterson, Donald G.; Turner, Wayman E.; Lee, Mary M.; Revich, Boris; Hauser, Russ B. (National Institute of Environmental Health Sciences, 2013)Background: Exposure to dioxins has been associated with delayed pubertal onset in both epidemiologic and animal studies. Whether genetic polymorphisms may modify this association is currently unknown. Identifying such ... -
High breast milk levels of polychlorinated biphenyls (PCBs) among four women living adjacent to a PCB-contaminated waste site
Korrick, Susan Abigail; Altshul, Larisa M. (National Institute of Environmental Health Sciences, 1998)As a consequence of contamination by effluents from local electronics manufacturing facilities, the New Bedford Harbor and estuary in southeastern Massachusetts is among the sites in the United States that are considered ... -
Measured Prenatal and Estimated Postnatal Levels of Polychlorinated Biphenyls (PCBs) and ADHD-Related Behaviors in 8-Year-Old Children
Verner, Marc-André; Hart, Jaime E.; Sagiv, Sharon K.; Bellinger, David C.; Altshul, Larisa M.; Korrick, Susan A. (NLM-Export, 2015)Background: Epidemiologic studies of postnatal PCB exposure and behavior have not reported consistent evidence of adverse associations, possibly because of challenges in exposure estimation. We previously developed a ... -
Neuropsychological Measures of Attention and Impulse Control among 8-Year-Old Children Exposed Prenatally to Organochlorines
Sagiv, Sharon K.; Thurston, Sally W.; Bellinger, David C.; Altshul, Larisa M.; Korrick, Susan Abigail (National Institute of Environmental Health Sciences, 2012)Background: We previously reported associations between organochlorines and behaviors related to attention deficit hyperactivity disorder among boys and girls at 8 years of age using a teacher’s rating scale for a birth ... -
Predictors of Serum Chlorinated Pesticide Concentrations among Prepubertal Russian Boys
Lam, Thuy; Williams, Paige L.; Burns, Jane S.; Sergeyev, Oleg; Korrick, Susan A.; Lee, Mary M.; Birnbaum, Linda S.; Revich, Boris; Altshul, Larisa M.; Patterson, Donald G.; Turner, Wayman E.; Hauser, Russ (National Institute of Environmental Health Sciences, 2013)Background: Few studies have evaluated predictors of childhood exposure to organochlorine pesticides (OCPs), a class of lipophilic persistent chemicals. Objectives: Our goal was to identify predictors of serum OCP ... -
Predictors of serum dioxin levels among adolescent boys in Chapaevsk, Russia: A cross-sectional pilot study
Hauser, Russ B.; Williams, Paige L.; Altshul, Larisa M.; Korrick, Susan Abigail; Peeples, Lynne; Patterson, Donald G; Turner, Wayman E; Lee, Mary M; Revich, Boris; Sergeyev, Oleg (BioMed Central, 2005)Background: Toxicological studies and limited human studies have demonstrated associations between exposure to polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls ... -
Prenatal Organochlorine and Methylmercury Exposure and Memory and Learning in School-Age Children in Communities Near the New Bedford Harbor Superfund Site, Massachusetts
Orenstein, Sara T.C.; Thurston, Sally W.; Bellinger, David C.; Schwartz, Joel D.; Amarasiriwardena, Chitra J.; Altshul, Larisa M.; Korrick, Susan A. (NLM-Export, 2014)Background: Polychlorinated biphenyls (PCBs), organochlorine pesticides, and methylmercury (MeHg) are environmentally persistent with adverse effects on neurodevelopment. However, especially among populations with commonly ... -
Prenatal Organochlorine Exposure and Measures of Behavior in Infancy Using the Neonatal Behavioral Assessment Scale (NBAS)
Sagiv, Sharon; Nugent, J. Kevin; Brazelton, Thomas Berry; Choi, Anna Lai; Tolbert, Paige E.; Altshul, Larisa M.; Korrick, Susan Abigail (National Institute of Environmental Health Sciences, 2008)Background: Previous literature suggests an association between organochlorines and behavioral measures in childhood, including inattention. Objective: This study was designed to assess whether prenatal organochlorine ... -
Prepubertal Serum Concentrations of Organochlorine Pesticides and Age at Sexual Maturity in Russian Boys
Lam, Thuy; Williams, Paige L.; Lee, Mary M.; Korrick, Susan A.; Birnbaum, Linda S.; Burns, Jane S.; Sergeyev, Oleg; Revich, Boris; Altshul, Larisa M.; Patterson, Donald G.; Hauser, Russ (National Institute of Environmental Health Sciences, 2015)Background: Few human studies have evaluated the impact of childhood exposure to organochlorine pesticides (OCP) on pubertal development. Objective: We evaluated associations of serum OCP concentrations [hexachlorobenzene ... -
The relationship between human semen parameters and environmental exposure to polychlorinated biphenyls and \(p,p'\)-DDE
Hauser, Russ B.; Chen, Zuying; Pothier, Lucille J.; Ryan, Louise Marie; Altshul, Larisa M. (2003)Scientific and public concern exists about potential reproductive health effects of persistent chlorinated organic chemicals, such as polychlorinated biphenyls (PCBs), dichlorodiphenyltrichloroethane (DDT), and ... -
The Relationship between Levels of PCBs and Pesticides in Human Hair and Blood: Preliminary Results
Altshul, Larisa M.; Covaci, Adrian; Hauser, Russ B. (National Institue of Environmental Health Sciences, 2004)Human hair as a biologic measure of exposure to persistent organic pollutants (POPs) has some advantages over the more commonly used blood and adipose tissue samples. However, one of the primary limitations is the difficulty ... -
Serum and follicular fluid concentrations of polybrominated diphenyl ethers and in-vitro fertilization outcome
Johnson, Paula I.; Altshul, Larisa M.; Cramer, Daniel William; Missmer, Stacey Ann; Hauser, Russ B.; Meeker, John D. (Elsevier BV, 2012)There is evidence of endocrine disruption and reproductive effects in animals following exposure to certain PBDEs, but human studies are limited. The goal of this study was to investigate the use of serum and follicular ... -
Serum and Follicular Fluid Organochlorine Concentrations Among Women Undergoing Assisted Reproduction Technologies
Meeker, John D; Missmer, Stacey Ann; Altshul, Larisa M.; Vitonis, Allison F; Ryan, Louise Marie; Cramer, Daniel William; Hauser, Russ B. (BioMed Central, 2009)Background: Exposure to persistent organic pollutants, including polychlorinated biphenyls (PCBs) and organochlorine pesticides, is widespread among the general population. There is evidence of adverse effects on reproduction ... -
Serum Concentrations of Organochlorine Pesticides and Growth among Russian Boys
Sergeyev, Oleg; Lee, Mary M.; Revich, Boris; Del Prato, Julie T.; Humblet, Olivier; Patterson, Donald G.; Turner, Wayman E.; Starovoytov, Mikhail; Burns, Jane S; Williams, Paige L.; Korrick, Susan Abigail; Altshul, Larisa M.; Hauser, Russ B. (National Institute of Environmental Health Sciences, 2011)Background: Limited human data suggest an association of organochlorine pesticides (OCPs) with adverse effects on children’s growth.: Objective: We evaluated the associations of OCPs with longitudinally assessed growth ... -
Serum Concentrations of Polychlorinated Biphenyls in Relation to in Vitro Fertilization Outcomes
Meeker, John D.; Maity, Arnab; Missmer, Stacey Ann; Williams, Paige L.; Mahalingaiah, Shruthi; Ehrlich, Shelley; Berry, Katharine F.; Altshul, Larisa M.; Perry, Melissa; Cramer, Daniel William; Hauser, Russ B. (Environmental Health Perspectives, 2011)Background: Human exposure to polychlorinated biphenyls (PCBs) remains widespread. PCBs have been associated with adverse reproductive health outcomes including reduced fecundability and increased risk of pregnancy loss, ...