Browsing by Author "Jeon, Hyesung"

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    • Architecture of Autoinhibited and Active BRAF–MEK1–14-3-3 Complexes 

      Rawson, Shaun; Kim, Byeong-Won; Sharif, Humayun; Jeon, Hyesung; Park, Eunyoung; Li, Kunhua; Ficarro, Scott; Gonzalez-De Pino, Gonzalo; Marto, Jarrod; Eck, Michael (Springer Science and Business Media LLC, 2019-10-03)
      RAF family kinases are RAS-activated switches that initiate signaling through the MAP kinase cascade to control cellular proliferation, differentiation and survival1-3. RAF activity is tightly regulated and inappropriate ...