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    • On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology 

      Chou, David; Frismantas, Viktoras; Milton, Yuka; David, Rhiannon; Pop-Damkov, Petar; Ferguson, Douglas; MacDonald, Alexander; Vargel Bolukbasi, Ozge; Joyce, Cailin E.; Moreira Teixeira, Liliana S.; Rech, Arianna; Jiang, Amanda; Calamari, Elizabeth; Jalili-Firoozinezhad, Sasan; Furlong, Brooke; O’Sullivan, Lucy R.; Ng, Carlos F.; Choe, Youngjae; Marquez, Susan; Myers, Kasiani C.; Weinberg, Olga K.; Hasserjian, Robert; Novak, Richard; Levy, Oren; Prantil-Baun, Rachelle; Novina, Carl; Shimamura, Akiko; Ewart, Lorna; Ingber, Donald (Springer Science and Business Media LLC, 2020-01-27)
      The inaccessibility of living bone marrow hampers the study of its pathophysiology under myelotoxic stress induced by drugs, radiation or genetic mutations. Here, we show that a vascularized human bone-marrow-on-a-chip ...