Now showing items 1-3 of 3

    • Neuregulin1-β Decreases IL-1β -Induced Neutrophil Adhesion to Human Brain Microvascular Endothelial Cells 

      Wu, Limin; Walas, Samantha; Leung, Wendy; Sykes, David Brian; Wu, Jiang; Lo, Eng H.; Lok, Josephine M. (Springer Nature, 2014)
      Neuroinflammation contributes to the pathophysiology of diverse diseases including stroke, traumatic brain injury, Alzheimer's Disease, Parkinson's Disease, and multiple sclerosis, resulting in neurodegeneration and loss ...
    • Neuroglobin-overexpression reduces traumatic brain lesion size in mice 

      Zhao, Song; Yu, Zhanyang; Xing, Changhong; Hayakawa, Kazuhide; Whalen, Michael Jerome; Lok, Josephine M.; Lo, Eng H.; Wang, Xiaoying (BioMed Central, 2012)
      Background: Accumulating evidence has demonstrated that over-expression of Neuroglobin (Ngb) is neuroprotective against hypoxic/ischemic brain injuries. In this study we tested the neuroprotective effects of Ngb over-expression ...
    • The Vasculome of the Mouse Brain 

      Guo, Shu-Zhen; Zhou, Yiming; Xing, Changhong; Lok, Josephine M.; Som, Angel T.; Ning, MingMing; Ji, Xunming; Lo, Eng H. (Public Library of Science, 2012)
      The blood vessel is no longer viewed as passive plumbing for the brain. Increasingly, experimental and clinical findings suggest that cerebral endothelium may possess endocrine and paracrine properties – actively releasing ...