Now showing items 1-2 of 2

    • Pneumococcal Population Dynamics in the Conjugate Vaccine Era 

      Mitchell, Patrick Kevin (2016-05-05)
      The introduction of pneumococcal conjugate vaccines (PCVs) in the early years of the 21st century have led to significant changes in pneumococcal epidemiology. Using transmission modeling and genomics based approaches, ...
    • Population genomics of post-vaccine changes in pneumococcal epidemiology 

      Croucher, Nicholas J.; Finkelstein, Jonathan A.; Pelton, Stephen I.; Mitchell, Patrick K.; Lee, Grace M.; Parkhill, Julian; Bentley, Stephen D.; Hanage, William P.; Lipsitch, Marc (2013)
      Whole genome sequencing of 616 asymptomatically carried pneumococci was used to study the impact of the 7-valent pneumococcal conjugate vaccine. Comparison of closely related isolates revealed the role of transformation ...