Browsing by Author "Durney, Michael"

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An Equilibrium-Dependent Retroviral mRNA Switch Regulates Translational Recoding

Houck-Loomis, Brian; Durney, Michael Anthony; Salguero, Carolina; Shankar, Neelaabh; Nagle, Julia Marie; Goff, Stephen; D'Souza, Victoria M (Nature Publishing Group, 2011)

Most retroviruses require translational recoding of a viral messenger RNA stop codon to maintain a precise ratio of structural (Gag) and enzymatic (Pol) proteins during virus assembly. Pol is expressed exclusively as a ...
Preformed Protein-Binding Motifs in 7SK snRNA: Structural and Thermodynamic Comparisons with Retroviral TAR

Durney, Michael Anthony; D'Souza, Victoria M. (Elsevier, 2010)

The 7SK small nuclear RNA is a highly conserved non-coding RNA that regulates transcriptional elongation. 7SK utilizes the HEXIM proteins to sequester the transcription factor P-TEFb by a mechanism similar to that used by ...