Browsing by Author "Menegas, William"

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    • Dopamine neurons projecting to the posterior striatum form an anatomically distinct subclass 

      Menegas, William; Bergan, Joseph F; Ogawa, Sachie K; Isogai, Yoh; Umadevi Venkataraju, Kannan; Osten, Pavel; Uchida, Naoshige; Watabe-Uchida, Mitsuko (eLife Sciences Publications, Ltd, 2015)
      Combining rabies-virus tracing, optical clearing (CLARITY), and whole-brain light-sheet imaging, we mapped the monosynaptic inputs to midbrain dopamine neurons projecting to different targets (different parts of the striatum, ...

    • Dopamine neurons projecting to the posterior striatum form an anatomically distinct subclass 

      Menegas, William; Bergan, Joseph F; Ogawa, Sachie K; Isogai, Yoh; Umadevi Venkataraju, Kannan; Osten, Pavel; Uchida, Naoshige; Watabe-Uchida, Mitsuko (eLife Sciences Publications, Ltd, 2015)
      Combining rabies-virus tracing, optical clearing (CLARITY), and whole-brain light-sheet imaging, we mapped the monosynaptic inputs to midbrain dopamine neurons projecting to different targets (different parts of the striatum, ...

    • Opposite initialization to novel cues in dopamine signaling in ventral and posterior striatum in mice 

      Menegas, William; Babayan, Benedicte M; Uchida, Naoshige; Watabe-Uchida, Mitsuko (eLife Sciences Publications, Ltd, 2017)
      Dopamine neurons are thought to encode novelty in addition to reward prediction error (the discrepancy between actual and predicted values). In this study, we compared dopamine activity across the striatum using fiber ...