Browsing by Author "Dickerson, Bradford"
Now showing items 1-7 of 7
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Biomarker-based prediction of progression in MCI: Comparison of AD signature and hippocampal volume with spinal fluid amyloid-β and tau
Dickerson, Bradford C.; Wolk, David A. (Frontiers Media S.A., 2013)Objective: New diagnostic criteria for mild cognitive impairment (MCI) due to Alzheimer's disease (AD) have been developed using biomarkers aiming to establish whether the clinical syndrome is likely due to underlying AD. ... -
The Cortical Signature of Alzheimer's Disease: Regionally Specific Cortical Thinning Relates to Symptom Severity in Very Mild to Mild AD Dementia and is Detectable in Asymptomatic Amyloid-Positive Individuals
Dickerson, Bradford Clark; Bakkour, Akram; Salat, David H.; Feczko, Eric; Pacheco, Jenni; Greve, Douglas N.; Grodstein, Francine; Wright, Christopher Ian; Blacker, Deborah Lynne; Rosas, Herminia Diana; Sperling, Reisa Anne; Atri, Alireza; Growdon, John Herbert; Hyman, Bradley Theodore; Morris, John C.; Fischl, Bruce R.; Buckner, Randy Lee (Oxford University Press, 2009)Alzheimer's disease (AD) is associated with neurodegeneration in vulnerable limbic and heteromodal regions of the cerebral cortex, detectable in vivo using magnetic resonance imaging. It is not clear whether abnormalities ... -
Differential Effects of Aging and Alzheimer's Disease on Medial Temporal Lobe Cortical Thickness and Surface Area
Dickerson, Bradford Clark; Feczko, Eric; Augustinack, Jean C.; Pacheco, Jenni; Morris, John C.; Fischl, Bruce; Buckner, Randy Lee (Elsevier, 2009)The volume of parcellated conical regions is a composite measure related to both thickness and surface area. It is not clear whether volumetric decreases in medial temporal lobe (MTL) cortical regions in aging and Alzheimer's ... -
Does amyloid deposition produce a specific atrophic signature in cognitively normal subjects?☆
Whitwell, Jennifer L.; Tosakulwong, Nirubol; Weigand, Stephen D.; Senjem, Matthew L.; Lowe, Val J.; Gunter, Jeffrey L.; Boeve, Bradley F.; Knopman, David S.; Dickerson, Bradford C.; Petersen, Ronald C.; Jack, Clifford R. (Elsevier, 2013)The objective of our study was to evaluate whether cognitively normal (CN) elderly participants showing elevated cortical beta-amyloid (Aβ) deposition have a consistent neuroanatomical signature of brain atrophy that may ... -
Fluid intelligence and brain functional organization in aging yoga and meditation practitioners
Gard, Tim; Taquet, Maxime; Dixit, Rohan; Hölzel, Britta K.; de Montjoye, Yves-Alexandre; Brach, Narayan; Salat, David H.; Dickerson, Bradford C.; Gray, Jeremy R.; Lazar, Sara W. (Frontiers Media S.A., 2014)Numerous studies have documented the normal age-related decline of neural structure, function, and cognitive performance. Preliminary evidence suggests that meditation may reduce decline in specific cognitive domains and ... -
Greater widespread functional connectivity of the caudate in older adults who practice kripalu yoga and vipassana meditation than in controls
Gard, Tim; Taquet, Maxime; Dixit, Rohan; Hölzel, Britta K.; Dickerson, Bradford C.; Lazar, Sara W. (Frontiers Media S.A., 2015)There has been a growing interest in understanding how contemplative practices affect brain functional organization. However, most studies have restricted their exploration to predefined networks. Furthermore, scientific ... -
Human middle longitudinal fascicle: segregation and behavioral-clinical implications of two distinct fiber connections linking temporal pole and superior temporal gyrus with the angular gyrus or superior parietal lobule using multi-tensor tractography
Makris, Nikolaos; Preti, M. G.; Wassermann, D.; Rathi, Yogesh; Papadimitriou, G. M.; Yergatian, C.; Dickerson, Bradford Clark; Shenton, Martha Elizabeth; Kubicki, Marek R. (Springer Science + Business Media, 2013)The middle longitudinal fascicle (MdLF) is a major fiber connection running principally between the superior temporal gyrus and the parietal lobe, neocortical regions of great biological and clinical interest. Although one ...