Now showing items 1-2 of 2

    • Nanog-like Regulates Endoderm Formation through the Mxtx2-Nodal Pathway 

      Xu, Cong; Fan, Zi Peng; Müller, Patrick; Fogley, Rachel; DiBiase, Anthony; Trompouki, Eirini; Unternaehrer, Juli; Xiong, Fengzhu; Torregroza, Ingrid; Evans, Todd; Megason, Sean; Daley, George Quentin; Schier, Alexander F; Young, Richard A.; Zon, Leonard Ira (Elsevier, 2012)
      In mammalian embryonic stem cells, the acquisition of pluripotency is dependent on Nanog, but the in vivo analysis of Nanog has been hampered by its requirement for early mouse development. In an effort to examine the role ...
    • Zebrafish Globin Switching Occurs in Two Developmental Stages and Is Controlled by the LCR 

      Ganis, Jared Jason; Hsia, Nelson; Trompouki, Eirini; de Jong, Jill L.O.; DiBiase, Anthony; Lambert, Janelle S.; Jia, Zhiying; Sabo, Peter J.; Weaver, Molly; Sandstrom, Richard; Stamatoyannopoulos, John A.; Zhou, Yi; Zon, Leonard Ira (Elsevier BV, 2012)
      Globin gene switching is a complex, highly regulated process allowing expression of distinct globin genes at specific developmental stages. Here, for the first time, we have characterized all of the zebrafish globins based ...