Now showing items 1-5 of 5

    • Anti-S1P Antibody as a Novel Therapeutic Strategy for VEGFR TKI-Resistant Renal Cancer 

      Zhang, Liang; Wang, Xiaoen; Bullock, Andrea; Callea, Marcella; Shah, H.; Song, Jiaxi; Moreno, K.; Visentin, B.; Deutschman, D.; Alsop, David; Atkins, M. B.; Mier, James; Signoretti, Sabina; Bhasin, Manoj; Sabbadini, R. A.; Bhatt, Rupal (American Association for Cancer Research (AACR), 2015-04-15)
      Purpose VEGFR2 tyrosine kinase inhibition (TKI) is a valuable treatment approach for patients with metastatic RCC. However, resistance to treatment is inevitable. Identification of novel targets could lead to better ...
    • Meta-analysis of transcriptome data identifies a novel 5-gene pancreatic adenocarcinoma classifier 

      Bhasin, Manoj K.; Ndebele, Kenneth; Bucur, Octavian; Yee, Eric U.; Otu, Hasan H.; Plati, Jessica; Bullock, Andrea; Gu, Xuesong; Castan, Eduardo; Zhang, Peng; Najarian, Robert; Muraru, Maria S.; Miksad, Rebecca; Khosravi-Far, Roya; Libermann, Towia A. (Impact Journals LLC, 2016)
      Purpose Pancreatic ductal adenocarcinoma (PDAC) is largely incurable due to late diagnosis. Superior early detection biomarkers are critical to improving PDAC survival and risk stratification. Experimental Design Optimized ...
    • The Role of Angiopoietins as Potential Therapeutic Targets in Renal Cell Carcinoma 

      Wang, Xiaoen; Bullock, Andrea; Zhang, Liang; Wei, Lin; Yu, Dongyin; Mahagaokar, Kedar; Alsop, David; Mier, James; Atkins, Michael B.; Coxon, Angela; Oliner, Jon; Bhatt, Rupal (Elsevier BV, 2014-04)
      Angiopoietin 2 (Ang2) is a secreted glycoprotein upregulated at sites of angiogenesis and has been implicated in cancer neovascularization. Recent studies have suggested efficacy of combined Ang and vascular endothelial ...
    • Stereotactic Body Radiotherapy (SBRT) for Intrahepatic and Hilar Cholangiocarcinoma 

      Mahadevan, Anand; Dagoglu, Nergiz; Mancias, Joseph; Raven, Kristin; Khwaja, Khalid; Tseng, Jennifer F; Ng, Kimmie; Enzinger, Peter; Miksad, Rebecca; Bullock, Andrea; Evenson, Amy (Ivyspring International Publisher, 2015)
      Background: Unresectable intrahepatic and hilar cholangiocarcinomas carry a dismal prognosis. Systemic chemotherapy and conventional external beam radiation and brachytherapy have been used with limited success. We explored ...
    • Stereotactic Body Radiotherapy (SBRT) Reirradiation for Recurrent Pancreas Cancer 

      Dagoglu, Nergiz; Callery, Mark; Moser, James; Tseng, Jennifer; Kent, Tara; Bullock, Andrea; Miksad, Rebecca; Mancias, Joseph D.; Mahadevan, Anand (Ivyspring International Publisher, 2016)
      Objectives: After adjuvant or definitive radiation for pancreas cancer, there are limited conventional treatment options for recurrent pancreas cancer. We explored the role of (Stereotactic Body Radiotherapy) SBRT for ...