Browsing by Author "Najarian, Robert M."

Now showing items 1-3 of 3

    • Fibroblast Growth Factor 21 (FGF21) Protects against High Fat Diet Induced Inflammation and Islet Hyperplasia in Pancreas 

      Singhal, Garima; Fisher, ffolliott Martin; Chee, Melissa J.; Tan, Tze Guan; El Ouaamari, Abdelfattah; Adams, Andrew C.; Najarian, Robert; Kulkarni, Rohit N.; Benoist, Christophe; Flier, Jeffrey S.; Maratos-Flier, Eleftheria (Public Library of Science, 2016)
      Fibroblast growth factor 21 (FGF21) is an important endocrine metabolic regulator expressed in multiple tissues including liver and adipose tissue. Although highest levels of expression are in pancreas, little is known ...

    • Meta-analysis of transcriptome data identifies a novel 5-gene pancreatic adenocarcinoma classifier 

      Bhasin, Manoj K.; Ndebele, Kenneth; Bucur, Octavian; Yee, Eric U.; Otu, Hasan H.; Plati, Jessica; Bullock, Andrea; Gu, Xuesong; Castan, Eduardo; Zhang, Peng; Najarian, Robert; Muraru, Maria S.; Miksad, Rebecca; Khosravi-Far, Roya; Libermann, Towia A. (Impact Journals LLC, 2016)
      Purpose Pancreatic ductal adenocarcinoma (PDAC) is largely incurable due to late diagnosis. Superior early detection biomarkers are critical to improving PDAC survival and risk stratification. Experimental Design Optimized ...

    • Reduced Intestinal Tumorigenesis in APCmin Mice Lacking Melanin-Concentrating Hormone 

      Nagel, Jutta M.; Geiger, Brenda Mae; Karagiannis, Apostolos K. A.; Gras-Miralles, Beatriz; Horst, David; Najarian, Robert; Ziogas, Dimitrios C.; Chen, Xinhua; Kokkotou, Efi G. (Public Library of Science, 2012)
      Background: Melanin-concentrating hormone (MCH) is an evolutionary conserved hypothalamic neuropeptide that in mammals primarily regulates appetite and energy balance. We have recently identified a novel role for MCH in ...