Browsing by Author "Xu, Shuyun"

Now showing items 1-3 of 3

    • 5-Hydroxymethylcytosine Expression in Metastatic Melanoma versus Nodal Nevus in Sentine Lymph Node Biopsies 

      Lee, Jonathan J.; Granter, Scott R.; Laga, Alvaro C.; Saavedra, Arturo; Zhan, Qian; Guo, Weimin; Xu, Shuyun; Murphy, George F.; Lian, Christine G. (2014)
      Sentinel lymph node biopsies are conducted to stage patients with newly-diagnosed melanomas that have histopathologic attributes conferring defined levels of metastatic potential. Because benign nevic cells may also form ...

    • Loss of the epigenetic mark, 5-Hydroxymethylcytosine, correlates with small cell/nevoid subpopulations and assists in microstaging of human melanoma 

      Lee, Jonathan J.; Cook, Martin; Mihm, Martin C.; Xu, Shuyun; Zhan, Qian; Wang, Thomas J.; Murphy, George F.; Lian, Christine G. (Impact Journals LLC, 2015)
      Melanomas in the vertical growth phase (VGP) not infrequently demonstrate cellular heterogeneity. One commonly encountered subpopulation displays small cell/nevoid morphology. Although its significance remains unknown, ...

    • Novel Genetic Mutations in a Sporadic Port-Wine Stain 

      Lian, Christine Guo; Sholl, Lynette Marie; Zakka, Labib; O, Teresa M.; Liu, Cynthia; Xu, Shuyun; Stanek, Ewelina; Garcia, Elizabeth; Jia, Yonghui; MacConaill, Laura Eleanor; Murphy, George Francis; Waner, Milton; Mihm, Martin Charles (American Medical Association (AMA), 2014)
      Importance Port-wine stains (PWSs) are common congenital cutaneous capillary malformations. A somatic GNAQ mutation was recently identified in patients with sporadic PWSs and Sturge-Weber syndrome. However, subsequent ...