Browsing by Author "Lange, Nancy E"

Now showing items 1-5 of 5

    • Alu and LINE-1 methylation and lung function in the normative ageing study 

      Lange, Nancy E; Sordillo, Joanne; Tarantini, Letizia; Bollati, Valentina; Sparrow, David; Vokonas, Pantel; Zanobetti, Antonella; Schwartz, Joel David; Baccarelli, Andrea; Litonjua, Augusto Ampil; Demeo, Dawn Lisa (BMJ Publishing Group, 2012)
      Objectives: To investigate the association between methylation of transposable elements Alu and long-interspersed nuclear elements (LINE-1) and lung function. Design: Cohort study. Setting: Outpatient Veterans Administration ...

    • Comprehensive Genetic Assessment of a Functional TLR9 Promoter Polymorphism: No Replicable Association with Asthma or Asthma-Related Phenotypes 

      Avila, Lydiana; Hawrylowicz, Catherine M; Lange, Nancy Elizabeth; Zhou, Xiaobo; Su, Jessica Ann Lasky; Himes, Blanca Elena; Lazarus, Ross; Raby, Benjamin Alexander; Litonjua, Augusto Ampil; Soto-Quiros, Manuel; Celedon, Juan C (BioMed Central, 2011)
      Background: Prior studies suggest a role for a variant (rs5743836) in the promoter of toll-like receptor 9 (TLR9) in asthma and other inflammatory diseases. We performed detailed genetic association studies of the functional ...

    • Maternal intestinal flora and wheeze in early childhood 

      Lange, Nancy; Celedón, Juan C.; Forno, Erick; Ly, Ngoc P.; Onderdonk, Andrew Bruce; Bry, Lynn; Delaney, Mary Louise Rodriguez; DuBois, Andrea M.; Gold, Diane R.; Weiss, Scott Tillman; Litonjua, Augusto Ampil (Wiley-Blackwell, 2011)
      Background: Increasing evidence links altered intestinal flora in infancy to eczema and asthma. No studies have investigated the influence of maternal intestinal flora on wheezing and eczema in early childhood. Objective: To ...

    • A Twin Study of Early-Childhood Asthma in Puerto Ricans 

      Bunyavanich, Supinda; Silberg, Judy L.; Lasky-Su, Jessica; Gillespie, Nathan A.; Lange, Nancy E.; Canino, Glorisa; Celedόn, Juan C. (Public Library of Science, 2013)
      Background: The relative contributions of genetics and environment to asthma in Hispanics or to asthma in children younger than 3 years are not well understood. Objective: To examine the relative contributions of genetics ...

    • The Vitamin D Antenatal Asthma Reduction Trial (VDAART): Rationale, design, and methods of a randomized, controlled trial of vitamin D supplementation in pregnancy for the primary prevention of asthma and allergies in children 

      Litonjua, Augusto Ampil; Lange, Nancy; Carey, Vincent James; Brown, Stacey; Laranjo, Nancy M; Harshfield, Benjamin J.; O'Conner, George; Sandel, Megan; Strunk, Robert C.; Bacharier, Leonard B.; Zeiger, Robert S.; Schatz, Michael; Hollis, Bruce W.; Weiss, Scott Tillman (Elsevier BV, 2014)
      There is intense interest in the role of vitamin D in the development of asthma and allergies. However, studies differ on whether a higher vitamin D intake or status in pregnancy or at birth is protective against asthma ...