Now showing items 1-2 of 2

    • A Chemical Genetic Approach Reveals Distinct Mechanisms of EphB Signaling During Brain Development 

      Soskis, Michael J.; Ho, Hsin-Yi Henry; Bloodgood, Brenda L.; Robichaux, Michael A.; Malik, Athar N.; Ataman, Bulent; Rubin, Alex A.; Zieg, Janine; Zhang, Chao; Shokat, Kevan M.; Sharma, Nikhil; Cowan, Christopher W.; Greenberg, Michael E. (2012)
      EphB receptor tyrosine kinases control multiple steps in nervous system development. However, it remains unclear whether EphBs regulate these different developmental processes directly or indirectly. In addition, as EphBs ...
    • Whole-Exome Sequencing and Homozygosity Analysis Implicate Depolarization-Regulated Neuronal Genes in Autism 

      Yu, Timothy W.; Lim, Elaine T.; Stevens, Christine R.; Gabriel, Stacey B.; Chahrour, Maria H.; Ataman, Bulent; Coulter, Michael Edward; Hill, Robert Sean; Schubert, Christian R.; Greenberg, Michael Eldon; Walsh, Christopher A. (Public Library of Science, 2012)
      Although autism has a clear genetic component, the high genetic heterogeneity of the disorder has been a challenge for the identification of causative genes. We used homozygosity analysis to identify probands from ...