Browsing by Author "Lopez, Lyle Villamater"
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A Mechanism for Vertebrate Hedgehog Signaling: Recruitment to Cilia and Dissociation of SuFu-Gli Protein Complexes
Tukachinsky, Hanna; Lopez, Lyle Vincent Villamater; Salic, Adrian (Rockefeller University Press, 2010)In vertebrates, Hedgehog (Hh) signaling initiated in primary cilia activates the membrane protein Smoothened (Smo) and leads to activation of Gli proteins, the transcriptional effectors of the pathway. In the absence of ... -
Regulation of Gli proteins by the Hedgehog Signaling Pathway
Lopez, Lyle Villamater (2013-10-17)Hedgehog signaling is essential during embryogenesis and in the maintenance of adult