Now showing items 1-4 of 4

    • Altered Host Immunity, Human T Lymphotropic Virus Type I Replication, and Risk of Adult T-Cell Leukemia/Lymphoma: A Prospective Analysis from the ATL Cohort Consortium 

      Okayama, Akihiko; Kim, Norma; Arisawa, Kokichi; Hanchard, Barrie; Inoue, Manami; Sawada, Takashi; Tsugane, Shoichiro; Li, Hongchuan; Hisada, Michie; Birmann, Brenda Melanie; Mueller, Nancy Elsa; Martínez-Maza, Otoniel; Breen, Elizabeth C.; Carneiro-Proietti, Anna B. F.; Falk, Kerstin I.; Murphy, Edward L.; Pfeiffer, Ruth M.; Stuver, Sherri O.; Suppan, Catherine A. (BioMed Central, 2011)
      Background: Adult T-cell leukemia/lymphoma (ATL) is a rare and often fatal outcome of infection with human T-lymphotropic virus type I (HTLV-I). Altered host immunity in HTLV-I carriers has been postulated as a risk factor ...
    • Epidemiologic Studies Assessing the Role of the Epstein-Barr Virus in Hodgkin's Disease 

      Mueller, Nancy Elsa (Yale Journal of Biology and Medicine, 1987)
      The hypothesis that an infection plays a role in the etiology of Hodgkin's disease (HD) is suggested by both its clinical and histologic features. Its bimodal age-incidence pattern also suggests an infectious process among ...
    • Overview: Viral Agents and Cancer. 

      Mueller, Nancy Elsa (The National Institute of Environmental Health Sciences, 1995)
      Substantial evidence indicates that several common viruses are clearly or probable causal factors in the etiology of specific malignancies. These viruses either normally establish latency or can become persistent infections. ...
    • Silencing of Human T-Cell Leukemia Virus Type I Gene Transcription by Epigenetic Mechanisms 

      Taniguchi, Yuko; Nosaka, Kisato; Yasunaga, Jun-ichirou; Maeda, Michiyuki; Mueller, Nancy Elsa; Okayama, Akihiko; Matsuoka, Masao (BioMed Central, 2005)
      Background: Human T-cell leukemia virus type I (HTLV-I) causes adult T-cell leukemia (ATL) after a long latent period. Among accessory genes encoded by HTLV-I, the tax gene is thought to play a central role in oncogenesis. ...