Now showing items 1-13 of 13

    • Association of Cumulative Lead Exposure with Parkinson’s Disease 

      Weisskopf, Marc G.; Weuve, Jennifer Lynn; Nie, Huiling; Saint-Hilaire, Marie-Helene; Sudarsky, Lewis Richard; Simon, David K.; Hersh, Bonnie Patricia; Schwartz, Joel David; Wright, Robert O.; Hu, Howard (National Institute of Environmental Health Sciences, 2010)
      Background: Research using reconstructed exposure histories has suggested an association between heavy metal exposures, including lead, and Parkinson’s disease (PD), but the only study that used bone lead, a biomarker of ...
    • Association of Environmental Cadmium Exposure with Pediatric Dental Caries 

      Arora, Manish; Weuve, Jennifer Lynn; Schwartz, Joel David; Wright, Robert O. (National Institute of Environmental Health Sciences, 2008)
      Background: Although animal experiments have shown that cadmium exposure results in severe dental caries, limited epidemiologic data are available on this issue. Objectives: We aimed to examine the relationship between ...
    • Association of Environmental Cadmium Exposure with Periodontal Disease in U.S. Adults 

      Arora, Manish; Weuve, Jennifer Lynn; Schwartz, Joel David; Wright, Robert O. (National Institute of Environmental Health Sciences, 2009)
      Background: Periodontal disease is a complex, multifactorial, chronic inflammatory disease that involves degradation of periodontal structures, including alveolar bone. Cadmium adversely affects bone remodeling, and it is ...
    • Association of Exposure to Phthalates with Endometriosis and Uterine Leiomyomata: Findings from NHANES, 1999–2004 

      Weuve, Jennifer Lynn; Hauser, Russ B.; Calafat, Antonia M.; Missmer, Stacey Ann; Wise, Lauren A. (National Institute of Environmental Health Sciences, 2010)
      Background: Phthalates are ubiquitous chemicals used in consumer products. Some phthalates are reproductive toxicants in experimental animals, but human data are limited. Objective: We conducted a cross-sectional study of ...
    • Blood Lead Levels and Major Depressive Disorder, Panic Disorder, and Generalized Anxiety Disorder in US Young Adults 

      Bouchard, Maryse F.; Bellinger, David C; Weuve, Jennifer; Matthews-Bellinger, Julia; Gilman, Stephen Edward; Wright, Robert O.; Schwartz, Joel David; Weisskopf, Marc G. (American Medical Association (AMA), 2009)
      CONTEXT: Lead is a ubiquitous neurotoxicant, and adverse cognitive and behavioral effects are well-documented in children and occupationally exposed adults but not in adults with low environmental exposure. OBJECTIVE: To ...
    • Cadmium Exposure and Neurodevelopmental Outcomes in U.S. Children 

      Ciesielski, Timothy; Weuve, Jennifer Lynn; Bellinger, David C.; Schwartz, Joel David; Lanphear, Bruce; Wright, Robert O. (National Institute of Environmental Health Sciences, 2012)
      Background: Low-level environmental cadmium exposure in children may be associated with adverse neurodevelopmental outcomes. Objective: Our aim was to evaluate associations between urinary cadmium concentration and reported ...
    • Cumulative Community-Level Lead Exposure and Pulse Pressure: The Normative Aging Study 

      Perlstein, Todd Steven; Weuve, Jennifer Lynn; Schwartz, Joel David; Sparrow, David; Wright, Robert O.; Litonjua, Augusto Ampil; Nie, Huiling; Hu, Howard (National Institute of Environmental Health Sciences, 2007)
      Background: Pulse pressure increases with age in industrialized societies as a manifestation of arterial stiffening. Lead accumulates in the vasculature and is associated with vascular oxidative stress, which can promote ...
    • Cumulative Exposure to Lead in Relation to Cognitive Function in Older Women 

      Weuve, Jennifer Lynn; Korrick, Susan Abigail; Weisskopf, Marc G.; Ryan, Louise Marie; Schwartz, Joel David; Nie, Huiling; Grodstein, Francine; Hu, Howard (National Institute of Environmental Health Sciences, 2008)
      Background: Recent data indicate that chronic low-level exposure to lead is associated with accelerated declines in cognition in older age, but this has not been examined in women. Objective: We examined biomarkers of lead ...
    • Cumulative Lead Exposure and Tooth Loss in Men: The Normative Aging Study 

      Arora, Manish; Weuve, Jennifer Lynn; Weisskopf, Marc G.; Sparrow, David; Nie, Huiling; Garcia, Raul I.; Hu, Howard (National Institute of Environmental Health Sciences, 2009)
      Background: Individuals previously exposed to lead remain at risk because of endogenous release of lead stored in their skeletal compartments. However, it is not known if long-term cumulative lead exposure is a risk factor ...
    • Exposure to Bisphenol A and Other Phenols in Neonatal Intensive Care Unit Premature Infants 

      Calafat, Antonia M.; Weuve, Jennifer Lynn; Ye, Xiaoyun; Jia, Lily T.; Hu, Howard; Ringer, Steven Alan; Huttner, Ken; Hauser, Russ B. (National Institute of Environmental Health Sciences, 2008)
      Objective: We previously demonstrated that exposure to polyvinyl chloride plastic medical devices containing di(2-ethylhexyl) phthalate (DEHP) was associated with higher urinary concentrations of several DEHP metabolites ...
    • Modifying Effects of the HFE Polymorphisms on the Association Between Lead Burden and Cognitive Decline 

      Wang, Florence T.; Hu, Howard; Schwartz, Joel David; Weuve, Jennifer Lynn; Spiro, Avron S.; Sparrow, David; Nie, Huiling; Silverman, Edwin Kepner; Weiss, Scott Tillman; Wright, Robert O. (National Institute of Environmental Health Sciences, 2007)
      Background: As iron and lead promote oxidative damage, and hemochromatosis (HFE) gene polymorphisms increase body iron burden, HFE variant alleles may modify the lead burden and cognitive decline relationship. Objective: ...
    • Relation of Cumulative Low-Level Lead Exposure to Depressive and Phobic Anxiety Symptom Scores in Middle-Age and Elderly Women 

      Eum, Ki-Do; Korrick, Susan Abigail; Weuve, Jennifer Lynn; Okereke, Olivia Ifeoma; Kubzansky, Laura Diane; Hu, Howard; Weisskopf, Marc G. (National Institute of Environmental Health Sciences, 2012)
      Background: Different lines of evidence suggest that low-level lead exposure could be a modifiable risk factor for adverse psychological symptoms, but little work has explored this relation. Objective: We assessed whether ...
    • Use of di(2-ethylhexyl) phthalate–containing medical products and urinary levels of mono(2-ethylhexyl) phthalate in neonatal intensive care unit infants 

      Green, Ronald; Hauser, Russ B.; Calafat, Antonia M.; Weuve, Jennifer Lynn; Schettler, Ted; Ringer, Steven Alan; Huttner, Kenneth; Hu, Howard (National Institute of Environmental Health Sciences, 2005)
      Objective: Di(2-ethylhexyl) phthalate (DEHP) is a plasticizer used in medical products made with polyvinyl chloride (PVC) plastic and may be toxic to humans. DEHP is lipophilic and binds non-covalently to PVC, allowing it ...