Browsing by Author "Bergholz, Johann"

Now showing items 1-1 of 1

    • PI3Kβ controls immune evasion in PTEN-deficient breast tumours 

      Bergholz, Johann; Wang, Qiwei; Wang, Qi; Ramseier, Michelle; Prakadan, Sanjay; Wang, Weihua; Fang, Rong; Kabraji, Sheheryar; Zhou, Qian; Gray, G. Kenneth; Abell-Hart, Kayley; Xie, Shaozhen; Guo, Xiaocan; Gu, Hao; Von, Thanh; Jiang, Tao; Tang, Shuang; Freeman, Gordon J.; Kim, Hye-Jung; Shalek, Alex K.; Roberts, Thomas M.; Zhao, Jean J. (Springer Science and Business Media LLC, 2023-04-19)
      Loss of the PTEN tumor suppressor is one of the most common oncogenic drivers across all cancer types. PTEN is the major negative regulator of phosphoinositide-3 kinase (PI3K) signaling. Notably, the PI3Kβ isoform has been ...