Browsing by Author "Branco, Alan"
Now showing items 1-4 of 4
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Chromatin-Associated Proteins HP1 and Mod(mdg4) Modify Y-Linked Regulatory Variation in the Drosophila Testis
Branco, Alan; Hartl, Daniel L.; Silva, Bernardo Lemos (Genetics Society of America, 2013)Chromatin remodeling is crucial for gene regulation. Remodeling is often mediated through chemical modifications of the DNA template, DNA-associated proteins, and RNA-mediated processes. Y-linked regulatory variation (YRV) ... -
Epigenetic Effects of Polymorphic Y Chromosomes Modulate Chromatin Components, Immune Response, and Sexual Conflict
Silva, Bernardo Lemos; Hartl, Daniel L.; Branco, Alan T. (National Academy of Sciences, 2010)Genetic conflicts between sexes and generations provide a foundation for understanding the functional evolution of sex chromosomes and sexually dimorphic phenotypes. Y chromosomes of Drosophila contain multi-megabase ... -
Natural Variation of the Y Chromosome Suppresses Sex Ratio Distortion and Modulates Testis-Specific Gene Expression in Drosophila Simulans
Branco, Alan; Tao, Y; Hartl, Daniel L.; Silva, Bernardo Lemos (Nature Publishing Group, 2013)X-linked sex-ratio distorters that disrupt spermatogenesis can cause a deficiency in functional Y-bearing sperm and a female-biased sex ratio. Y-linked modifiers that restore a normal sex ratio might be abundant and favored ... -
Ribosomal DNA Deletions Modulate Genome-Wide Gene Expression: ‘‘rDNA–Sensitive’’ Genes and Natural Variation
Hartl, Daniel L.; Paredes, Silvana; Branco, Alan; Maggert, Keith A.; Silva, Bernardo Lemos (Public Library of Science, 2011)The ribosomal rDNA gene array is an epigenetically-regulated repeated gene locus. While rDNA copy number varies widely between and within species, the functional consequences of subtle copy number polymorphisms have been ...