Now showing items 1-4 of 4

    • Caveolin 1 Modulates Aldosterone‐Mediated Pathways of Glucose and Lipid Homeostasis 

      Baudrand, Rene; Gupta, Nidhi; Garza, Amanda E.; Vaidya, Anand; Leopold, Jane A.; Hopkins, Paul N.; Jeunemaitre, Xavier; Ferri, Claudio; Romero, Jose R.; Williams, Jonathan; Loscalzo, Joseph; Adler, Gail K.; Williams, Gordon H.; Pojoga, Luminita H. (John Wiley and Sons Inc., 2016)
      Background: Overactivation of the aldosterone and mineralocorticoid receptor (MR) pathway is associated with hyperglycemia and dyslipidemia. Caveolin 1 (cav‐1) is involved in glucose/lipid homeostasis and may modulate MR ...
    • HPA Axis Genetic Variation, Cortisol, and Psychosis in Major Depression 

      Schatzberg, Alan F.; Keller, Jennifer; Tennakoon, Lakshika; Lembke, Anna; Williams, Gordon; Kraemer, Fredric B.; Sarginson, Jane E.; Lazzeroni, Laura C.; Murphy, Greer M. (2013)
      Genetic variation underlying hypothalamic pituitary adrenal (HPA) axis over-activity in healthy controls and patients with severe forms of major depression has not been well explored but could explain risk for cortisol ...
    • No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels 

      Scott, Robert A.; Chu, Audrey Yu-lei; Grarup, Niels; Manning, Alisa K.; Hivert, Marie-France; Shungin, Dmitry; Tönjes, Anke; Yesupriya, Ajay; Barnes, Daniel; Bouatia-Naji, Nabila; Glazer, Nicole L.; Jackson, Anne U.; Kutalik, Zoltán; Lagou, Vasiliki; Marek, Diana; Rasmussen-Torvik, Laura J.; Stringham, Heather M.; Tanaka, Toshiko; Aadahl, Mette; Arking, Dan E.; Bergmann, Sven; Boerwinkle, Eric; Bonnycastle, Lori L.; Bornstein, Stefan R.; Brunner, Eric; Bumpstead, Suzannah J.; Brage, Soren; Carlson, Olga D.; Chen, Han; Chen, Yii-Der Ida; Chines, Peter S.; Collins, Francis S.; Couper, David J.; Dennison, Elaine M.; Dowling, Nicole F.; Egan, Josephine S.; Ekelund, Ulf; Erdos, Michael R.; Forouhi, Nita G.; Fox, Caroline; Goodarzi, Mark O.; Grässler, Jürgen; Gustafsson, Stefan; Hallmans, Göran; Hansen, Torben; Hingorani, Aroon; Holloway, John W.; Hu, Frank B.; Isomaa, Bo; Jameson, Karen A.; Johansson, Ingegerd; Jonsson, Anna; Jørgensen, Torben; Kivimaki, Mika; Kovacs, Peter; Kumari, Meena; Kuusisto, Johanna; Laakso, Markku; Lecoeur, Cécile; Lévy-Marchal, Claire; Li, Guo; Loos, Ruth J.F.; Lyssenko, Valeri; Marmot, Michael; Marques-Vidal, Pedro; Morken, Mario A.; Müller, Gabriele; North, Kari E.; Pankow, James S.; Payne, Felicity; Prokopenko, Inga; Psaty, Bruce M.; Renström, Frida; Rice, Ken; Rotter, Jerome I.; Rybin, Denis; Sandholt, Camilla H.; Sayer, Avan A.; Shrader, Peter; Schwarz, Peter E.H.; Siscovick, David S.; Stančáková, Alena; Stumvoll, Michael; Teslovich, Tanya M.; Waeber, Gérard; Williams, Gordon Harold; Witte, Daniel R.; Wood, Andrew R.; Xie, Weijia; Boehnke, Michael; Cooper, Cyrus; Ferrucci, Luigi; Froguel, Philippe; Groop, Leif; Kao, W.H. Linda; Vollenweider, Peter; Walker, Mark; Watanabe, Richard M.; Pedersen, Oluf; Meigs, James Benjamin; Ingelsson, Erik; Barroso, Inês; Florez, Jose Carlos; Franks, Paul W.; Dupuis, Josée; Wareham, Nicholas J.; Langenberg, Claudia (American Diabetes Association, 2012)
      Gene–lifestyle interactions have been suggested to contribute to the development of type 2 diabetes. Glucose levels 2 h after a standard 75-g glucose challenge are used to diagnose diabetes and are associated with both ...
    • Patiromer induces rapid and sustained potassium lowering in patients with chronic kidney disease and hyperkalemia 

      Bushinsky, David A; Williams, Gordon H; Pitt, Bertram; Weir, Matthew R; Freeman, Mason W; Garza, Dahlia; Stasiv, Yuri; Li, Elizabeth; Berman, Lance; Bakris, George L (Nature Publishing Group, 2015)
      Patients with chronic kidney disease (CKD) have a high risk of hyperkalemia, which increases mortality and can lead to renin–angiotensin–aldosterone system inhibitor (RAASi) dose reduction or discontinuation. Patiromer, a ...