Browsing by Author "Nakashima, Hiroshi"
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Redesigned Reporter Gene for Improved Proton Exchange-Based Molecular MRI Contrast
Perlman, Or; Ito, Hirotaka; Gilad, Assaf A.; McMahon, Michael T.; Chiocca, E.; Nakashima, Hiroshi; Farrar, Christian (Springer Science and Business Media LLC, 2020-11-26)Reporter gene imaging allows for non-invasive monitoring of molecular processes in living cells, providing insights on the mechanisms underlying pathology and therapy. A lysine-rich protein (LRP) chemical exchange saturation ... -
Toxicology and Biodistribution Studies for MGH2.1, an Oncolytic Virus that Expresses Two Prodrug-activating Genes, in Combination with Prodrugs
Kasai, Kazue; Nakashima, Hiroshi; Liu, Fang; Kerr, Samantha; Wang, Jiang; Phelps, Mitch; Potter, Philip M; Goins, William B; Fernandez, Soledad A; Chiocca, E Antonio (Nature Publishing Group, 2013)MGH2.1 is a herpes simplex virus type 1 (HSV1) oncolytic virus that expresses two prodrug-activating transgenes: the cyclophosphamide (CPA)-activating cytochrome P4502B1 (CYP2B1) and the CPT11-activating secreted human ...