Now showing items 1-4 of 4

    • AC and AG Dinucleotide Repeats in the PAX6 P1 Promoter are Associated with High Myopia 

      Ng, Tsz Kin; Lam, Ching Yan; Lam, Dennis Shun Chiu; Chiang, Sylvia Wai Yee; Tam, Pancy Oi Sin; Yam, Gary Hin-Fai; Fan, Dorothy Shu Ping; Pang, Chi Pui; Wang, Danyi; Fan, Baojian (Molecular Vision, 2009)
      Purpose: The PAX6 gene, located at the reported myopia locus MYP7 on chromosome 11p13, was postulated to be associated with myopia development. This study investigated the association of PAX6 with high myopia in 379 high ...
    • Common Variants at 9p21 and 8q22 Are Associated with Increased Susceptibility to Optic Nerve Degeneration in Glaucoma 

      Yaspan, Brian L.; Hauser, Michael A.; Allingham, R. Rand; Olson, Lana M.; Abdrabou, Wael; Brodeur, Wendy; Budenz, Donald L.; Caprioli, Joseph; Crenshaw, Andrew; Crooks, Kristy; DelBono, Elizabeth; Doheny, Kimberly F.; Gaasterland, Douglas; Gaasterland, Terry; Laurie, Cathy; Lichter, Paul R.; Loomis, Stephanie; Liu, Yutao; Medeiros, Felipe A.; McCarty, Cathy; Mirel, Daniel; Moroi, Sayoko E.; Musch, David C.; Realini, Anthony; Rozsa, Frank W.; Schuman, Joel S.; Scott, Kathleen; Singh, Kuldev; Trager, Edward H.; VanVeldhuisen, Paul; Vollrath, Douglas; Wollstein, Gadi; Yoneyama, Sachiko; Zhang, Kang; Weinreb, Robert N.; Ernst, Jason; Masuda, Tomohiro; Zack, Don; Richards, Julia E.; Pericak-Vance, Margaret; Haines, Jonathan L.; Wiggs, Janey Lee; Kang, Jae Hee Hee; Fan, Baojian; Wang, Danyi; Friedman, David S.; Lee, Richard K.; Stein, Joshua D.; Kellis, Manolis; Pasquale, Louis (Public Library of Science, 2012)
      Optic nerve degeneration caused by glaucoma is a leading cause of blindness worldwide. Patients affected by the normal-pressure form of glaucoma are more likely to harbor risk alleles for glaucoma-related optic nerve ...
    • Different WDR36 Mutation Pattern in Chinese Patients with Primary Open-angle Glaucoma 

      Fan, Baojian; Wang, Danyi; Cheng, Ching-Yu; Ko, Wendy Charles; Lam, Shun Chiu; Pang, Chi Pui (Molecular Vision, 2009)
      Purpose: To determine the distribution of WD repeat domain 36 (WDR36) sequence variants in Chinese patients with primary open-angle glaucoma (POAG). Methods: One hundred and thirty-five unrelated POAG patients (82 high ...
    • The p53 Codon 72 PRO/PRO Genotype May Be Associated with Initial Central Visual Field Defects in Caucasians with Primary Open Angle Glaucoma 

      Wiggs, Janey Lee; Hewitt, Alex W.; Fan, Baojian; Wang, Danyi; Figueiredo Sena, Dayse R.; O’Brien, Colm; Realini, Anthony; Craig, Jamie E.; Dimasi, David P.; Mackey, David A.; Haines, Jonathan L.; Pasquale, Louis (Public Library of Science, 2012)
      Background: Loss of vision in glaucoma is due to apoptotic retinal ganglion cell loss. While p53 modulates apoptosis, gene association studies between p53 variants and glaucoma have been inconsistent. In this study we ...