Now showing items 1-2 of 2

    • EspA Acts as a Critical Mediator of ESX1-Dependent Virulence in Mycobacterium tuberculosis by Affecting Bacterial Cell Wall Integrity 

      Garces, Alejandra; Woodworth, Joshua S.; Krastins, Bryan; Atmakuri, Krishnamohan; Chase, Michael Richard; Rothchild, Alissa C.; Ramsdell, Talia Lynn; Lopez, Mary Frances; Behar, Samuel M; Sarracino, David A.; Fortune, Sarah Merritt (Public Library of Science, 2010)
      Mycobacterium tuberculosis (Mtb) requires the ESX1 specialized protein secretion system for virulence, for triggering cytosolic immune surveillance pathways, and for priming an optimal CD8+ T cell response. This suggests ...
    • Molecular Motors of ESX-Type Secretion Systems 

      Ramsdell, Talia Lynn (2012-12-17)
      Tuberculosis is an enormous global health problem. Despite decades of research, the mechanism(s) by which Mycobacterium tuberculosis (Mtb) mediates virulence remains incompletely understood. The ESX-1 secretion system is ...