Now showing items 1-6 of 6

    • 2001: A Mouse Genome Odyssey 

      Beier, David Randolph; Herron, Bruce J (BioMed Central, 2002)
      A report on the 15th International Mouse Genome Conference, Edinburgh, UK, 21-24 October 2001.
    • Fog2 is required for normal diaphragm and lung development in mice and humans 

      Ackerman, Kate G; Herron, Bruce J; Huang, Hailu; Tevosian, Sergei G; Kochilas, Lazaros; Rao, Cherie; Babiuk, Randal P; Epstein, Jonathan A; Greer, John J; Vargas, Sara Oakes; Pober, Barbara R.; Beier, David Randolph (Public Library of Science, 2005)
      Congenital diaphragmatic hernia and other congenital diaphragmatic defects are associated with significant mortality and morbidity in neonates; however, the molecular basis of these developmental anomalies is unknown. In ...
    • The IFT-A Complex Regulates Shh Signaling through Cilia Structure and Membrane Protein Trafficking 

      Liem, Karel F., Jr.; Ashe, Alyson; He, Mu; Satir, Peter; Moran, Jennifer; Beier, David Randolph; Wicking, Carol; Anderson, Kathryn V. (The Rockefeller University Press, 2012)
      Two intraflagellar transport (IFT) complexes, IFT-A and IFT-B, build and maintain primary cilia and are required for activity of the Sonic hedgehog (Shh) pathway. A weak allele of the IFT-A gene, Ift144, caused subtle ...
    • Production of a Natural Antibody to the Mouse Polyoma Virus Is a Multigenic Trait 

      Andrews, Erik; Velupillai, Palanivel; Sung, Chang Kyoo; Beier, David Randolph; Benjamin, Thomas L. (Genetics Society of America, 2012)
      MA/MyJ mice express a natural antibody to the highly oncogenic polyoma virus. C57BR/cdJ mice lack this antibody but mount an adaptive T-cell response to the virus. Analysis of F2 progeny of a cross between these strains ...
    • A Spontaneous Fatp4/Scl27a4 Splice Site Mutation in a New Murine Model for Congenital Ichthyosis 

      Tao, Jianning; Koster, Maranke I.; Harrison, Wilbur; Moran, Jennifer L.; Beier, David R.; Roop, Dennis R.; Overbeek, Paul A. (Public Library of Science, 2012)
      Congenital ichthyoses are life-threatening conditions in humans. We describe here the identification and molecular characterization of a novel recessive mutation in mice that results in newborn lethality with severe ...
    • A Transient Transgenic RNAi Strategy for Rapid Characterization of Gene Function during Embryonic Development 

      Bjork, Bryan Cary; Fujiwara, Yuko; Davis, Shannon W.; Qiu, Haiyan; Saunders, Thomas L.; Sandy, Peter; Orkin, Stuart Holland; Camper, Sally A.; Beier, David Randolph (Public Library of Science, 2010)
      RNA interference (RNAi) is a powerful strategy for studying the phenotypic consequences of reduced gene expression levels in model systems. To develop a method for the rapid characterization of the developmental consequences ...