Browsing by Author "Jang, Yongwoo"
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Amniotic fluid exerts a neurotrophic influence on fetal neurodevelopment via the ERK/GSK-3 pathway
Jang, Yongwoo; Kim, Eun-Kyung; Shim, Won-Sik; Song, Ki-Min; Kim, Sung Min (BioMed Central, 2015)Background: The fetus is surrounded by the amniotic fluid (AF) contained by the amniotic sac of the pregnant female. The AF is directly conveyed to the fetus during pregnancy. Although AF has recently been reported as an ... -
The RAB39B p.G192R mutation causes X-linked dominant Parkinson’s disease
Mata, Ignacio F.; Jang, Yongwoo; Kim, Chun-Hyung; Hanna, David S.; Dorschner, Michael O.; Samii, Ali; Agarwal, Pinky; Roberts, John W.; Klepitskaya, Olga; Shprecher, David R.; Chung, Kathryn A.; Factor, Stewart A.; Espay, Alberto J.; Revilla, Fredy J.; Higgins, Donald S.; Litvan, Irene; Leverenz, James B.; Yearout, Dora; Inca-Martinez, Miguel; Martinez, Erica; Thompson, Tiffany R.; Cholerton, Brenna A.; Hu, Shu-Ching; Edwards, Karen L.; Kim, Kwang-Soo; Zabetian, Cyrus P. (BioMed Central, 2015)Objective: To identify the causal gene in a multi-incident U.S. kindred with Parkinson’s disease (PD). Methods: We characterized a family with a classical PD phenotype in which 7 individuals (5 males and 2 females) were ... -
Red ginseng extract blocks histamine-dependent itch by inhibition of H1R/TRPV1 pathway in sensory neurons
Jang, Yongwoo; Lee, Wook-Joo; Hong, Gyu-Sang; Shim, Won-Sik (Elsevier, 2015)Background: Korean Red Ginseng—a steamed root of Panax ginseng Meyer—has long been used as a traditional medicine in Asian countries. Its antipruritic effect was recently found, but no molecular mechanisms were revealed. ...