Browsing by Author "Kong, Jian"
Now showing items 1-20 of 25
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Altered periaqueductal gray resting state functional connectivity in migraine and the modulation effect of treatment
Li, Zhengjie; Liu, Mailan; Lan, Lei; Zeng, Fang; Makris, Nikos; Liang, Yilin; Guo, Taipin; Wu, Feng; Gao, Yujie; Dong, Mingkai; Yang, Jie; Li, Ying; Gong, Qiyong; Liang, Fanrong; Kong, Jian (Nature Publishing Group, 2016)The aims of this study were to 1) compare resting state functional connectivity (rs-fc) of the periaqueductal gray (PAG), a key region in the descending pain modulatory system (DPMS) between migraine without aura (MwoA) ... -
Are All Placebo Effects Equal? Placebo Pills, Sham Acupuncture, Cue Conditioning and Their Association
Kong, Jian; Spaeth, Rosa; Cook, Amanda; Kirsch, Irving; Claggett, Brian; Vangel, Mark; Gollub, Randy L.; Smoller, Jordan W.; Kaptchuk, Ted J. (Public Library of Science, 2013)Placebo treatments and healing rituals have been used to treat pain throughout history. The present within-subject crossover study examines the variability in individual responses to placebo treatment with verbal suggestion ... -
Changes of functional connectivity in the left frontoparietal network following aphasic stroke
Zhu, Dan; Chang, Jingling; Freeman, Sonya; Tan, Zhongjian; Xiao, Juan; Gao, Ying; Kong, Jian (Frontiers Media S.A., 2014)Language is an essential higher cognitive function supported by large-scale brain networks. In this study, we investigated functional connectivity changes in the left frontoparietal network (LFPN), a language-cognition ... -
Default mode network connectivity encodes clinical pain: An arterial spin labeling study
Loggia, Marco Luciano; Kim, Jieun; Gollub, Randy Lyanne; Vangel, Mark G.; Kirsch, Irving; Kong, Jian; Wasan, Ajay D.; Napadow, Vitaly J. (Ovid Technologies (Wolters Kluwer Health), 2013)Neuroimaging studies have suggested the presence of alterations in the anatomo-functional properties of the brain of patients with chronic pain. However, investigation of the brain circuitry supporting the perception of ... -
Deqi Sensations of Transcutaneous Electrical Nerve Stimulation on Auricular Points
Wang, Xiaoling; Fang, Jiliang; Zhao, Qing; Fan, Yangyang; Liu, Jun; Hong, Yang; Wang, Honghong; Ma, Yunyao; Xu, Chunhua; Shi, Shan; Kong, Jian; Rong, Peijing (Hindawi Publishing Corporation, 2013)Deqi sensation, a psychophysical response characterized by a spectrum of different needling sensations, is essential for Chinese acupuncture clinical efficacy. Previous research works have investigated the component of ... -
Design of a randomised acupuncture trial on functional neck/shoulder stiffness with two placebo controls
Takakura, Nobuari; Takayama, Miho; Kawase, Akiko; Kaptchuk, Ted J; Kong, Jian; Yajima, Hiroyoshi (BioMed Central, 2014)Background: Functional neck/shoulder stiffness is one of the most well-known indications for acupuncture treatment in Japan. There is little evidence for the effectiveness of acupuncture treatment for functional neck/shoulder ... -
Disrupted functional connectivity of the periaqueductal gray in chronic low back pain
Yu, Rongjun; Gollub, Randy L.; Spaeth, Rosa; Napadow, Vitaly; Wasan, Ajay; Kong, Jian (Elsevier, 2014)Chronic low back pain is a common neurological disorder. The periaqueductal gray (PAG) plays a key role in the descending modulation of pain. In this study, we investigated brain resting state PAG functional connectivity ... -
Effect of transcutaneous auricular vagus nerve stimulation on impaired glucose tolerance: a pilot randomized study
Huang, Feng; Dong, Jianxun; Kong, Jian; Wang, Hongcai; Meng, Hong; Spaeth, Rosa B; Camhi, Stephanie; Liao, Xing; Li, Xia; Zhai, Xu; Li, Shaoyuan; Zhu, Bing; Rong, Peijing (BioMed Central, 2014)Background: Impaired glucose tolerance (IGT) is a pre-diabetic state of hyperglycemia that is associated with insulin resistance, increased risk of type II diabetes, and cardiovascular pathology. Recently, investigators ... -
Imaging the Functional Connectivity of the Periaqueductal Gray During Genuine and Sham Electroacupuncture Treatment
Zyloney, Carolyn E; Jensen, Karin; Polich, Ginger; Loiotile, Rita E; Cheetham, Alexandra; LaViolette, Peter S; Tu, Peichi; Kaptchuk, Ted Jack; Gollub, Randy L.; Kong, Jian (BioMed Central, 2010)Background: Electroacupuncture (EA) is currently one of the most popular acupuncture modalities. However, the continuous stimulation characteristic of EA treatment presents challenges to the use of conventional functional ... -
Increased Hippocampus–Medial Prefrontal Cortex Resting-State Functional Connectivity and Memory Function after Tai Chi Chuan Practice in Elder Adults
Tao, Jing; Liu, Jiao; Egorova, Natalia; Chen, Xiangli; Sun, Sharon; Xue, Xiehua; Huang, Jia; Zheng, Guohua; Wang, Qin; Chen, Lidian; Kong, Jian (Frontiers Media S.A., 2016)Previous studies provide evidence that aging is associated with the decline of memory function and alterations in the hippocampal (HPC) function, including functional connectivity to the medial prefrontal cortex (mPFC). ... -
A Longitudinal Study of the Reliability of Acupuncture Deqi Sensations in Knee Osteoarthritis
Spaeth, Rosa B.; Camhi, Stephanie; Hashmi, Javeria A.; Vangel, Mark; Wasan, Ajay D.; Edwards, Robert R.; Gollub, Randy L.; Kong, Jian (Hindawi Publishing Corporation, 2013)Deqi is one of the core concepts in acupuncture theory and encompasses a range of sensations. In this study, we used the MGH Acupuncture Sensation Scale (MASS) to measure and assess the reliability of the sensations evoked ... -
The modulation effect of longitudinal acupuncture on resting state functional connectivity in knee osteoarthritis patients
Chen, Xiaoyan; Spaeth, Rosa B.; Freeman, Sonya G.; Scarborough, Donna Moxley; Hashmi, Javeria A.; Wey, Hsiao-Ying; Egorova, Natalia; Vangel, Mark; Mao, Jianren; Wasan, Ajay D.; Edwards, Robert R.; Gollub, Randy L.; Kong, Jian (BioMed Central, 2015)Recent advances in brain imaging have contributed to our understanding of the neural activity associated with acupuncture treatment. In this study, we investigated functional connectivity across longitudinal acupuncture ... -
Neural Correlates of Chronic Low Back Pain Measured by Arterial Spin Labeling
Wasan, Ajay D.; Loggia, Marco Luciano; Chen, Li Q.; Napadow, Vitaly J.; Kong, Jian; Gollub, Randy Lyanne (Ovid Technologies (Wolters Kluwer Health), 2011)Background The varying nature of chronic pain (CP) is difficult to correlate to neural activity using typical functional magnetic resonance imaging methods. Arterial spin labeling is a perfusion-based imaging technique ... -
A Neural Mechanism for Nonconscious Activation of Conditioned Placebo and Nocebo Responses
Jensen, Karin B.; Kaptchuk, Ted J.; Chen, Xiaoyan; Kirsch, Irving; Ingvar, Martin; Gollub, Randy L.; Kong, Jian (Oxford University Press, 2014)Fundamental aspects of human behavior operate outside of conscious awareness. Yet, theories of conditioned responses in humans, such as placebo and nocebo effects on pain, have a strong emphasis on conscious recognition ... -
Neurochemical changes in patients with chronic low back pain detected by proton magnetic resonance spectroscopy: A systematic review
Zhao, Xianjing; Xu, Maosheng; Jorgenson, Kristen; Kong, Jian (Elsevier, 2016)Background: Low back pain is a highly prevalent health problem around the world, affecting 50% to 85% of people at some point in life. The purpose of this systematic review is to summarize the previous proton magnetic ... -
Not seeing or feeling is still believing: conscious and non-conscious pain modulation after direct and observational learning
Egorova, Natalia; Park, Joel; Orr, Scott P.; Kirsch, Irving; Gollub, Randy L.; Kong, Jian (Nature Publishing Group, 2015)Our experience with the world is shaped not only directly through personal exposure but also indirectly through observing others and learning from their experiences. Using a conditioning paradigm, we investigated how ... -
P02.146. Mindfulness Based Stress Reduction in Adults with Mild Cognitive Impairment: A Pilot Study Using fMRI
Wells, R; Kerr, C; Wolkin, J; Wall, R; Kong, Jian; Yeh, Gloria Y.; Press, Daniel; Kaptchuk, Ted Jack; Davis, R.; Tan, Y.; Walsh, J.; Phillips, R. (BioMed Central, 2012) -
Patients with fibromyalgia display less functional connectivity in the brain’s pain inhibitory network
Jensen, Karin; Loitoile, Rita; Kosek, Eva; Petzke, Frank; Carville, Serena; Fransson, Peter; Marcus, Hanke; Williams, Steven CR; Choy, Ernest; Mainguy, Yves; Vitton, Olivier; Gracely, Richard H; Gollub, Randy L.; Ingvar, Martin; Kong, Jian (BioMed Central, 2012)Background: There is evidence for augmented processing of pain and impaired endogenous pain inhibition in Fibromyalgia syndrome (FM). In order to fully understand the mechanisms involved in FM pathology, there is a need ... -
Phenotype Matters: The Absence of a Positive Association Between Cortical Thinning and Chronic Low Back Pain When Controlling for Salient Clinical Variables
Dolman, Andrew J.; Loggia, Marco Luciano; Edwards, Robert R; Gollub, Randy Lyanne; Kong, Jian; Napadow, Vitaly J.; Wasan, Ajay D. (Ovid Technologies (Wolters Kluwer Health), 2014)Studies have associated chronic low back pain (cLBP) with grey matter thinning. But these studies have not controlled for important clinical variables (such as a comorbid affective disorder, pain medication, age, or pain ... -
Placebo Acupuncture Devices: Considerations for Acupuncture Research
Zhu, Dan; Gao, Ying; Chang, Jingling; Kong, Jian (Hindawi Publishing Corporation, 2013)Determining an appropriate control for use in acupuncture research remains one of the largest methodological challenges acupuncture researchers face. In general, acupuncture controls fall under one of two categories: (1) ...