Now showing items 1-7 of 7

    • Characterizing the Cancer Genome in Lung Adenocarcinoma 

      Weir, Barbara A.; Woo, Michele S.; Getz, Gad; Perner, Sven; Ding, Li; Beroukhim, Rameen; Lin, William; Province, Michael A.; Kraja, Aldi T.; Johnson, Laura A.; Shah, Kinjal; Sato, Mitsuo; Thomas, Roman K.; Barletta, Justine; Borecki, Ingrid B.; Broderick, Stephen; Chang, Andrew C.; Chiang, Derek Y.; Chirieac, Lucian; Cho, Jeonghee; Fujii, Yoshitaka; Gazdar, Adi F.; Giordano, Thomas J.; Greulich, Heidi; Hanna, Megan; Johnson, Bruce; Kris, Mark G.; Lash, Alex; Lin, Ling; Lindeman, Neal; Mardis, Elaine R.; McPherson, John D.; Minna, John D.; Morgan, Margaret B.; Nadel, Mark; Orringer, Mark B.; Osborne, John R.; Ozenberger, Brad; Ramos, Alex H.; Robinson, James; Roth, Jack A.; Rusch, Valerie; Sasaki, Hidefumi; Shepherd, Frances A.; Sougnez, Carrie; Spitz, Margaret R.; Tsao, Ming-Sound; Twomey, David; Verhaak, Roel G. W.; Weinstock, George; Wheeler, David A.; Winckler, Wendy; Yoshizawa, Akihiko; Yu, Soyoung; Zakowski, Maureen F.; Zhang, Qunyuan; Beer, David G.; Wistuba, Ignacio I.; Watson, Mark A.; Garraway, Levi A.; Ladanyi, Marc; Travis, William D.; Pao, William; Rubin, Mark A; Gabriel, Stacey; Gibbs, Richard A.; Varmus, Harold E.; Wilson, Richard K.; Lander, Eric; Meyerson, Matthew (Springer Science and Business Media LLC, 2007-12-06)
      Somatic alterations in cellular DNA underlie almost all human cancers1. The prospect of targeted therapies2 and the development of high-resolution, genome-wide approaches3–8 are now spurring systematic efforts to characterize ...
    • Collagen XXIII: A Potential Biomarker for the Detection of Primary and Recurrent Non–Small Cell Lung Cancer 

      Spivey, Kristin A.; Banyard, Jacqueline; Solis, Luisa M.; Wistuba, Ignacio I.; Barletta, Justine; Gandhi, Leena; Feldman, Henry; Rodig, Scott; Chirieac, Lucian; Zetter, Bruce (American Association for Cancer Research (AACR), 2010-05)
      Background Collagen XXIII is a transmembrane collagen previously shown to be upregulated in metastatic prostate cancer. This study’s purpose was to determine the protein expression of collagen XXIII in tumor tissues from ...
    • FGFR3 expression in primary and metastatic urothelial carcinoma of the bladder 

      Guancial, Elizabeth A; Werner, Lillian; Bellmunt, Joaquim; Bamias, Aristotle; Choueiri, Toni K; Ross, Robert; Schutz, Fabio A; Park, Rachel S; O'Brien, Robert J; Hirsch, Michelle S; Barletta, Justine A; Berman, David M; Lis, Rosina; Loda, Massimo; Stack, Edward C; Garraway, Levi A; Riester, Markus; Michor, Franziska; Kantoff, Philip W; Rosenberg, Jonathan E (BlackWell Publishing Ltd, 2014)
      While fibroblast growth factor receptor 3 (FGFR3) is frequently mutated or overexpressed in nonmuscle-invasive urothelial carcinoma (UC), the prevalence of FGFR3 protein expression and mutation remains unknown in muscle-invasive ...
    • The Prognostic Significance of Grading in Lung Adenocarcinoma 

      Barletta, Justine; Yeap, Beow; Chirieac, Lucian (2010-02-01)
      Background Although grading has prognostic significance for many tumor types, a prognostically significant grading system for lung adenocarcinoma has not yet been established. The aim of this study was to evaluate histologic ...
    • Sox2 Protein Expression is an Independent Poor Prognostic Indicator in Stage I Lung Adenocarcinoma 

      Sholl, Lynette Marie; Barletta, Justine Anastasia; Yeap, Beow Yong; Chirieac, Lucian Radu; Hornick, Jason L. (Ovid Technologies (Wolters Kluwer Health), 2010)
      Many patients with stage I non-small cell lung carcinoma will develop recurrence following surgical excision. Sox2 is a marker of embryonic stem cell pluripotency that is associated with aggressive tumor behavior and is ...
    • Unique Clinicopathologic Features Characterize ALK-Rearranged Lung Adenocarcinoma in the Western Population 

      Rodig, Scott; Mino-Kenudson, Mari; Dacic, Sanja; Yeap, Beow; Shaw, Alice; Barletta, Justine; Stubbs, Hannah; Law, Kenny; Lindeman, Neal; Mark, Eugene; Janne, Pasi; Lynch, Thomas; Johnson, Bruce; Iafrate, Anthony; Chirieac, Lucian (American Association for Cancer Research (AACR), 2009-08-15)
      Purpose The anaplastic large cell kinase gene (ALK) is rearranged in approximately 5% of lung adenocarcinomas within the Asian population. We evaluated the incidence and the characteristics of ALK-rearranged lung ...
    • The variable phenotype and low-risk nature of RAS-positive thyroid nodules 

      Medici, Marco; Kwong, Norra; Angell, Trevor E.; Marqusee, Ellen; Kim, Matthew I.; Frates, Mary C.; Benson, Carol B.; Cibas, Edmund S.; Barletta, Justine A.; Krane, Jeffrey F.; Ruan, Daniel T.; Cho, Nancy L.; Gawande, Atul A.; Moore, Francis D.; Alexander, Erik K. (BioMed Central, 2015)
      Background: Oncogenic mutations are common in thyroid cancers. While the frequently detected RAS-oncogene mutations have been studied for diagnostic use in cytologically indeterminate thyroid nodules, no investigation has ...