Browsing by Author "Haberer, Jessica"
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Adherence to Antiretroviral Prophylaxis for HIV Prevention: A Substudy Cohort within a Clinical Trial of Serodiscordant Couples in East Africa
Haberer, Jessica E.; Baeten, Jared M.; Campbell, James; Wangisi, Jonathan; Katabira, Elly; Ronald, Allan; Tumwesigye, Elioda; Psaros, Christina; Safren, Steven A.; Ware, Norma C.; Thomas, Katherine K.; Donnell, Deborah; Krows, Meighan; Kidoguchi, Lara; Celum, Connie; Bangsberg, David R. (Public Library of Science, 2013)Background: Randomized clinical trials of oral antiretroviral pre-exposure prophylaxis (PrEP) for HIV prevention have widely divergent efficacy estimates, ranging from 0% to 75%. These discrepancies are likely due to ... -
Caregiver Perceptions and Motivation for Disclosing or Concealing the Diagnosis of HIV Infection to Children Receiving HIV Care in Mbarara, Uganda: A Qualitative Study
Kiwanuka, Julius; Mulogo, Edgar; Haberer, Jessica E. (Public Library of Science, 2014)Background: Disclosure of the diagnosis of HIV to HIV-infected children is challenging for caregivers. Despite current recommendations, data suggest that levels of disclosure of HIV status to HIV-infected children receiving ... -
A combination SMS and transportation reimbursement intervention to improve HIV care following abnormal CD4 test results in rural Uganda: a prospective observational cohort study
Siedner, Mark J.; Santorino, Data; Lankowski, Alexander J.; Kanyesigye, Michael; Bwana, Mwebesa B.; Haberer, Jessica E.; Bangsberg, David R. (BioMed Central, 2015)Background: Up to 50 % of HIV-infected persons in sub-Saharan Africa are lost from care between HIV diagnosis and antiretroviral therapy (ART) initiation. Structural barriers, including cost of transportation to clinic and ... -
Comparison of Self-Reported Alcohol Consumption to Phosphatidylethanol Measurement among HIV-Infected Patients Initiating Antiretroviral Treatment in Southwestern Uganda
Bajunirwe, Francis; Haberer, Jessica E.; Boum, Yap; Hunt, Peter; Mocello, Rain; Martin, Jeffrey N.; Bangsberg, David R.; Hahn, Judith A. (Public Library of Science, 2014)Background: Alcohol consumption among HIV-infected patients may accelerate HIV disease progression or reduce antiretroviral therapy adherence. Self-reported alcohol use is frequently under-reported due to social desirability ... -
Counseling Framework for HIV-Serodiscordant Couples on the Integrated Use of Antiretroviral Therapy and Pre-exposure Prophylaxis for HIV Prevention
Morton, Jennifer F.; Celum, Connie; Njoroge, John; Nakyanzi, Agnes; Wakhungu, Imeldah; Tindimwebwa, Edna; Ongachi, Snaidah; Sedah, Eric; Okwero, Emmanuel; Ngure, Kenneth; Odoyo, Josephine; Bulya, Nulu; Haberer, Jessica E.; Baeten, Jared M.; Heffron, Renee (JAIDS Journal of Acquired Immune Deficiency Syndromes, 2016)Background: For HIV-serodiscordant couples, integrated delivery of antiretroviral therapy (ART) for HIV-positive partners and time-limited pre-exposure prophylaxis (PrEP) for negative partners virtually eliminates HIV ... -
Depression During Pregnancy and the Postpartum Among HIV-Infected Women on Antiretroviral Therapy in Uganda
Kaida, Angela; Matthews, Lynn T.; Ashaba, Scholastic; Tsai, Alexander C.; Kanters, Steve; Robak, Magdalena; Psaros, Christina; Kabakyenga, Jerome; Boum, Yap; Haberer, Jessica E.; Martin, Jeffrey N.; Hunt, Peter W.; Bangsberg, David R. (JAIDS Journal of Acquired Immune Deficiency Syndromes, 2014)Background: Among HIV-infected women, perinatal depression compromises clinical, maternal, and child health outcomes. Antiretroviral therapy (ART) is associated with lower depression symptom severity but the uniformity of ... -
Dissemination of Research Findings to Research Participants Living with HIV in Rural Uganda: Challenges and Rewards
Baylor, Anna; Muzoora, Conrad; Bwana, Mwebsa; Kembabazi, Annet; Haberer, Jessica; Matthews, Lynn Turner; Tsai, Alexander Chung-Yu; Hunt, Peter K.; Martin, Jeffrey N.; Bangsberg, David Roy (Public Library of Science, 2013)David Bangsberg and colleagues explore the challenges and rewards of sharing research findings with participants living with HIV enrolled in observational research in rural sub-Saharan Africa. -
Empiric Deworming and CD4 Count Recovery in HIV-Infected Ugandans Initiating Antiretroviral Therapy
Lankowski, Alexander J.; Tsai, Alexander C.; Kanyesigye, Michael; Bwana, Mwebesa; Haberer, Jessica E.; Wenger, Megan; Martin, Jeffrey N.; Bangsberg, David R.; Hunt, Peter W.; Siedner, Mark J. (Public Library of Science, 2014)Background: There is conflicting evidence on the immunologic benefit of treating helminth co-infections (“deworming”) in HIV-infected individuals. Several studies have documented reduced viral load and increased CD4 count ... -
High acceptability for cell phone text messages to improve communication of laboratory results with HIV-infected patients in rural Uganda: a cross-sectional survey study
Siedner, Mark Jacob; Haberer, Jessica; Bwana, Mwebesa Bosco; Ware, Norma Clara; Bangsberg, David Roy (BioMed Central, 2012)Background: Patient-provider communication is a major challenge in resource-limited settings with large catchment areas. Though mobile phone usership increased 20-fold in Africa over the past decade, little is known about ... -
HIV Protective Efficacy and Correlates of Tenofovir Blood Concentrations in a Clinical Trial of PrEP for HIV Prevention
Donnell, Deborah; Baeten, Jared M.; Bumpus, Namandjé N.; Brantley, Justin; Bangsberg, David R.; Haberer, Jessica E.; Mujugira, Andrew; Mugo, Nelly; Ndase, Patrick; Hendrix, Craig; Celum, Connie (JAIDS Journal of Acquired Immune Deficiency Syndromes, 2014)Background: Antiretroviral pre-exposure prophylaxis (PrEP) is a novel HIV prevention strategy for which adherence is a known determinant of efficacy. Blood concentrations of PrEP medications are one objective marker of ... -
Incidence and Predictors of Pregnancy among a Cohort of HIV-Positive Women Initiating Antiretroviral Therapy in Mbarara, Uganda
Kaida, Angela; Matthews, Lynn Turner; Kanters, Steve; Kabakyenga, Jerome; Muzoora, Conrad; Mocello, A. Rain; Martin, Jeffrey N.; Hunt, Peter; Haberer, Jessica; Hogg, Robert S.; Bangsberg, David Roy (Public Library of Science, 2013)Objective: Many people living with HIV in sub-Saharan Africa desire biological children. Implementation of HIV prevention strategies that support the reproductive goals of people living with HIV while minimizing HIV ... -
Integrated Delivery of Antiretroviral Treatment and Pre-exposure Prophylaxis to HIV-1–Serodiscordant Couples: A Prospective Implementation Study in Kenya and Uganda
Baeten, Jared M.; Heffron, Renee; Kidoguchi, Lara; Mugo, Nelly R.; Katabira, Elly; Bukusi, Elizabeth A.; Asiimwe, Stephen; Haberer, Jessica E.; Morton, Jennifer; Ngure, Kenneth; Bulya, Nulu; Odoyo, Josephine; Tindimwebwa, Edna; Hendrix, Craig; Marzinke, Mark A.; Ware, Norma C.; Wyatt, Monique A.; Morrison, Susan; Haugen, Harald; Mujugira, Andrew; Donnell, Deborah; Celum, Connie (Public Library of Science, 2016)Background: Antiretroviral-based interventions for HIV-1 prevention, including antiretroviral therapy (ART) to reduce the infectiousness of HIV-1 infected persons and pre-exposure prophylaxis (PrEP) to reduce the susceptibility ... -
Intimate Partner Violence and Adherence to HIV Pre-exposure Prophylaxis (PrEP) in African Women in HIV Serodiscordant Relationships: A Prospective Cohort Study
Roberts, Sarah T.; Haberer, Jessica; Celum, Connie; Mugo, Nelly; Ware, Norma C.; Cohen, Craig R.; Tappero, Jordan W.; Kiarie, James; Ronald, Allan; Mujugira, Andrew; Tumwesigye, Elioda; Were, Edwin; Irungu, Elizabeth; Baeten, Jared M. (JAIDS Journal of Acquired Immune Deficiency Syndromes, 2016)Background: Intimate partner violence (IPV) is associated with higher HIV incidence, reduced condom use, and poor adherence to antiretroviral therapy and other medications. IPV may also affect adherence to pre-exposure ... -
Lay Social Resources for Support of Adherence to Antiretroviral Prophylaxis for HIV Prevention Among Serodiscordant Couples in sub-Saharan Africa: A Qualitative Study
Ware, Norma C.; Pisarski, Emily E.; Haberer, Jessica E.; Wyatt, Monique A.; Tumwesigye, Elioda; Baeten, Jared M.; Celum, Connie L.; Bangsberg, David R. (Springer US, 2014)Effectiveness of antiretroviral pre-exposure prophylaxis (PrEP) for HIV prevention will require high adherence. Using qualitative data, this paper identifies potential lay social resources for support of PrEP adherence by ... -
The Meanings in the messages: how SMS reminders and real-time adherence monitoring improve antiretroviral therapy adherence in rural Uganda
Ware, Norma C.; Pisarski, Emily E.; Tam, Melanie; Wyatt, Monique A.; Atukunda, Esther; Musiimenta, Angella; Bangsberg, David R.; Haberer, Jessica E. (Lippincott Williams & Wilkins, 2016)Objective: To understand how a pilot intervention combining SMS reminders with real-time adherence monitoring improved adherence to HIV antiretroviral therapy (ART) for adults initiating treatment in rural Uganda. Design: ... -
Multiple Measures Reveal Antiretroviral Adherence Successes and Challenges in HIV-Infected Ugandan Children
Haberer, Jessica; Kiwanuka, Julius; Nansera, Denis; Ragland, Kathleen; Mellins, Claude; Bangsberg, David Roy (Public Library of Science, 2012)Background: Adherence to HIV antiretroviral therapy (ART) among children in developing settings is poorly understood. Methodology/Principal Findings: To understand the level, distribution, and correlates of ART adherence ... -
Optimizing Network Connectivity for Mobile Health Technologies in sub-Saharan Africa
Siedner, Mark Jacob; Lankowski, Alexander; Musinga, Derrick; Jackson, Jonathon; Muzoora, Conrad; Hunt, Peter W.; Martin, Jeffrey N.; Bangsberg, David Roy; Haberer, Jessica (Public Library of Science, 2012)Background: Mobile health (mHealth) technologies hold incredible promise to improve healthcare delivery in resource-limited settings. Network reliability across large catchment areas can be a major challenge. We performed ... -
A Pilot Study of an mHealth Application for Healthcare Workers: Poor Uptake Despite High Reported Acceptability at a Rural South African Community-Based MDR-TB Treatment Program
Chaiyachati, Krisda H.; Loveday, Marian; Lorenz, Stephen; Lesh, Neal; Larkan, Lee-Megan; Cinti, Sandro; Friedland, Gerald H.; Haberer, Jessica (Public Library of Science, 2013)Introduction: As the South African province of KwaZulu-Natal addresses a growing multidrug-resistant tuberculosis (MDR-TB) epidemic by shifting care and treatment from trained specialty centers to community hospitals, ... -
Real-Time Adherence Monitoring for HIV Antiretroviral Therapy
Haberer, Jessica; Kahane, Josh; Kigozi, Isaac; Emenyonu, Nneka; Hunt, Peter K.; Martin, Jeffrey; Bangsberg, David Roy (Springer US, 2010)Current adherence assessments typically detect missed doses long after they occur. Real-time, wireless monitoring strategies for antiretroviral therapy may provide novel opportunities to proactively prevent virologic rebound ... -
Rethinking the “Pre” in Pre-Therapy Counseling: No Benefit of Additional Visits Prior to Therapy on Adherence or Viremia in Ugandans Initiating ARVs
Lankowski, Alexander; Kembabazi, Annet; Emenyonu, Nneka; Muzoora, Conrad; Geng, Elvin; Martin, Jeffrey N.; Siedner, Mark Jacob; Haberer; Haberer, Jessica; Tsai, Alexander Chung-Yu; Bangsberg, David Roy (Public Library of Science, 2012)Background: Many guidelines recommend adherence counseling prior to initiating antiretrovirals (ARVs), however the additional benefit of pre-therapy counseling visits on early adherence is not known. We sought to assess ...