Browsing by Author "Schwarzschild, Michael"
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Meeting Report: Consensus Statement—Parkinson’s Disease and the Environment: Collaborative on Health and the Environment and Parkinson’s Action Network (CHE PAN) Conference 26–28 June 2007.
Bronstein, Jeff; Carvey, Paul; Chen, Honglei; Cory-Slechta, Deborah; DiMonte, Donato; Duda, John; English, Paul; Grate, Stephen; Hansen, Johnni; Hoppin, Jane; Jewell, Sarah; Kamel, Freya; Koroshetz, Walter; Langston, James W.; Logroscino, Giancarlo; Nelson, Lorene; Ravina, Bernard; Rocca, Walter; Schettler, Ted; Scott, Bill; Seegal, Richard; Singleton, Andrew; Steenland, Kyle; Tanner, Caroline M.; Van Den Eeden, Stephen; Goldman, Samuel; Ross, George W.; Schwarzschild, Michael Alan; Weisskopf, Marc G. (National Institute of Environmental Health Sciences, 2008)Background: Parkinson’s disease (PD) is the second most common neurodegenerative disorder. People with PD, their families, scientists, health care providers, and the general public are increasingly interested in identifying ... -
Particulate matter and risk of parkinson disease in a large prospective study of women
Palacios, Natalia; Fitzgerald, Kathryn C; Hart, Jaime E; Weisskopf, Marc G; Schwarzschild, Michael A; Ascherio, Alberto; Laden, Francine (BioMed Central, 2014)Background: Exposure to air pollution has been implicated in a number of adverse health outcomes and the effect of particulate matter (PM) on the brain is beginning to be recognized. Yet, no prospective study has examined ... -
A Prospective Analysis of Airborne Metal Exposures and Risk of Parkinson Disease in the Nurses’ Health Study Cohort
Palacios, Natalia; Fitzgerald, Kathryn; Roberts, Andrea L.; Hart, Jaime E.; Weisskopf, Marc G.; Schwarzschild, Michael A.; Ascherio, Alberto; Laden, Francine (NLM-Export, 2014)Background: Exposure to metals has been implicated in the pathogenesis of Parkinson disease (PD). Objectives: We sought to examine in a large prospective study of female nurses whether exposure to airborne metals was ... -
The Sirtuin-2 Inhibitor AK7 Is Neuroprotective in Models of Parkinson’s Disease but Not Amyotrophic Lateral Sclerosis and Cerebral Ischemia
Chen, Xiqun; Wales, Pauline; Quinti, Luisa; Zuo, Fuxing; Moniot, Sébastien; Herisson, Fanny; Rauf, Nazifa Abdul; Wang, Hua; Silverman, Richard B.; Ayata, Cenk; Maxwell, Michelle M.; Steegborn, Clemens; Schwarzschild, Michael A.; Outeiro, Tiago F.; Kazantsev, Aleksey G. (Public Library of Science, 2015)Sirtuin deacetylases regulate diverse cellular pathways and influence disease processes. Our previous studies identified the brain-enriched sirtuin-2 (SIRT2) deacetylase as a potential drug target to counteract neurodegeneration. ...